Gleason 7 downgraded to 6 following RP in 2002, as prostate was very large, tumor smaller than estimated. No positive margins, surgeon reported fairly large negative margins remained. PSA undetectable for 2 years, gradually rising, now at .5. I also have Hepatitis C, was on transplant list, but as a result of rising PSA I have been removed from the list. My urologist says my prostate tissue could be causing the PSA rise but I could actually be cancer free. I am trying to get reinstated to the transplant list. Would a blood test for CTC definitively say if I have recurrent prostate cancer or not?
Thank you for your question. CTC tests are for assessment of progression of metastatic disease, rather than the presence of metastatic disease. The cause of a PSA rise needs to be addressed prior to making an assessment on the progression of metastatic disease. Imaging studies, should be performed as well.
Ash K. Tewari, MD
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