Thank you for your question. Nearly all prostate cancers become resistant to hormone therapy after a few months or years of treatment. In short, hormone therapies should be reevaluated after the PSA starts to rise. If you are currently taking bicalutamide you could switch to flutamide or nilutamide. The next step may be to move to secondary therapy ketoconazole.
It is important to continue to watch the PSA along with imagining to monitor bone activity.
Thank you for your question. To help me better answer your question, please respond with response to the following:
1) Is this your first line of anti-androgen therapy, have you been on a LHRH agonist 2) what are your testosterone levels 3) what is your age 4) did you have surgery or radiation or any other interventions?
Ashutosh (Ash) K. Tewari, MD
www.cornellroboticprostate.org
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