Treatment Ketoconazole

[slippery618]

I have been on ketoconazole and a steriod for one week now for advanced prostate cancer.  I have had removal, hormone therapy, radiation and now this.  I feel very sick and nausiated.  I am going to discontinue this ketoconazole.  I will call Dr. tomorrow.  What happens next?  Chemo?  If I were to continue on Ketoconazole would I get over this very sick and nausiated feeling?  Please someone help me with some answers from someone who has been there.

[francis1702]

A related discussion, CICLOFOSFAMIDA AND PRENIDSONA, WII IT WORK was started.

[slippery618]

My Dr took me off of the steriod and left me on ketoconazole twice a day.  So last evening I had tightness in my chest and a weird jaw feeling.  In looked at the side effects of the ketoconazole and it said tightness of the chest could happen.  Now I stopped taking it and called the Dr.  He now wants to see me in a couple days.  What is next?  Was it really the Keoconazole or was I having some kind of heart attack?  I did not go to emergency because the discomfort went away.

[Ash Tewari, MD, M.Ch.]

Thank you for your question. Nausea related to ketoconazole usually improves over time. It is inadvisable for patients on ketoconazole to self-medicate with acid-blocking medications, antacids, or other over-the-counter (non-prescription) items without consulting a physician. Because stomach acid is necessary for absorption of HDK, use of antacids will limit HDK’s effectiveness.

Best of luck

Ashutosh (Ash) K. Tewari, MD
www.cornellroboticprostate.org

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