I had a MRI of my left knee, due to some knee pain. Report reads: "There is a heterogeneous marrow pattern with areas of abnormal marrow signal in the posterior tibial metaphysis and anterior femoral metaphysis. A patchy abnormal marrow signal in the femor and the tibia could represent leukemic infiltration or heterogeneous red marrow reconversion"
I am currently 2 years in remission from Acute Lymphocyctic Leukemia, and 6 months away from finishing maintenance chemotherapy. My oncologist, said he discussed the report with other radiologists, and they feel the cancer is not coming back. I followed up with the orthopaedic doctor, and he has no idea why I came back to him, and said that there was no dead bone cells in my knee and he cleared me.
Should I be concerned about the possibility of leukemic infiltrates? If so, why hasn't my oncologist stopped me for further testing?
Normal bone marrow has yellow marrow and red marrow. Yellow marrow is more of fat and red marrow is more of haematopoitic tissue. in infants marrow is predominantly hematopoietic with the exception of epiphyses & apophyses, which are predominantly fatty throughout life. with skeletal growth, red marrow is gradually replaced by fat. red marrow persistis longer in the vertebrae, pelvic bones, sternum, & proximal ends of the long tubular bones, during normal marrow conversion, residual islands of red marrow may subsist in the yellow marrow, as may fatty foci in red marrow.islands of red marrow residue may be a normal variant especially in obese women, cigarette smokers, marathon runners. It may be pathological some times in cases of hemolytic processes / anemia.
However in your case u already have leukemia and altered signal in the marrow may indicate red marrow reconversion or leukemic infiltrates and on MRI alone it is difficult to say what is the possibility. Your oncologist is the best judge.
Copyright 1994-2018MedHelp.All rights reserved. MedHelp is a division of Vitals Consumer Services, LLC.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.