Dr. Nicolson, are there any clinical trials for patients with Langerhan's Cell Histiocytosis that are adults? Is this disease autoimmune or cancer or both? Dispite trying to maintain activity levels I find myself tired all of the time, swollen with any activity the day after, and in excutiating pain...from spinal cord injuries or this disease? or both? I can't keep weight on, and my teeth are once again beginning to rot from the inside out...doesn't this in itself cause a person to feel ill and fatigued? Grrr., some diffinitive answers and constant medical care that would be up to date on my case would be a nice idea but seems to be out of the question since I am over the age of 18. I've had several infectious disease such as parasites, valley fever, giardia, mold growing in my sinus cavities, etc....you name it it would seem I have had it.