Aa
Aa
A
A
A
Close
Avatar universal

looking for a suitable anti inflammatory for MAO deficiency

They both have chronic CRP index of between 20 to 30. The only thing I have been able to find to help is lysozyme chloride but it has varying effect. Paracetamol is less helpful but helps at times. I am convinced that it is an auto immune response to the constantly elevated adrenalin but need help to find possible alternatives.my wige and son are both effected.
1 Responses
Sort by: Helpful Oldest Newest
1530171 tn?1448129593
-The MAO-A in the brain can be influenced.
-Sirtuins are MAO-A modulators.
-SIRT1 activates MAO-A and decreases serotonin via deacetylation of NHLH2
Source: https://doi.org/10.1016/j.cell.2011.10.054

Suggestions for addressing Low MAO-A, modulating adrenaline levels and reducing inflammation.

1. Optimize SIRT1 levels.
2.  Normalize circardian rhythm.
3. Exercise daily but before 7 pm
4. Take ample sun (to increase Vit. D and Nitric Oxide)
5. . Nicotinamide adenine dinucleotide (NAD+) is a necessary co-enzyme for SIRT1 to work
6. Highest quality possible of B complex (containing Methyfolate and Methylocobalamin B12)
7. DHA & EPA Omega-3s from Krill oil.
8. Eliminate all junk food & pro-inflammatory cooking oils  Use coconut oil which does not degrade with heat.
9. Reduce carbs (anything with sugar, grains, flours etc.
is pro-inflammatory)
10. Increase cellular levels of magnesium.
Magnesium modulates cellular events involved in inflammation
Magnesium chloride (oral and transdermal) is the best source.

Best wishes,
Niko
Helpful - 0
1 Comments
Thank you for the suggestions. I will definitely research further!
Have an Answer?

You are reading content posted in the Rare Diseases Community

Didn't find the answer you were looking for?
Ask a question
Popular Resources
New study links cell phones to slightly increased cancer risk. Should you be concerned?
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.
Condoms are the most effective way to prevent HIV and STDs.