What would be the difference in a chest x-ray of early cystic fibrosis vs reactive airway.
Background: My oldest daughter died of CF 8 years ago. Her younger sister is a known carrier & her husband has never been tested. Their daughter's newborn screen was negative. The baby is now 1 y.o. and has had frequent upper respiratory infections & ear infections. Frequent non-productive cough. Recent CXR showed a "thickening" of the lungs. My daughter is a respiratory therapist & thinks this is more indicative of CF rather than RAD? Is this correct? Is it possible the newborn screen missed the CF? My daughter's defective gene in delta F 508. If the baby had this gene & a gene from Dad that is less common for CF would it show up on the newborn screen?
A chest x-ray may show bronchial wall thickening with either disease but the estimation of such thickening is semi-quantitative at best. CT scanning of the lungs is much more sensitive. One should not reach any conclusions about the diagnosis of asthma or cystic fibrosis (CF), on the basis of equivocal chest x-ray findings. Genetic testing is reliable but there is variability in the number of genes tested for from one laboratory to another, and thus it is conceivable that she may have an undetected CF gene, from her father.
She may have CF or asthma, both or neither and it behooves you and her doctor to have this clarified by a pediatric pulmonologist, preferably one with a special interest in CF.
You would be able to get a much more definitive answer to your question from any well-established, university medical center CF clinic doctor. I strongly suggest that you ask your granddaughter’s pediatrician for referral to a CF clinic. Everyone in your family will be less anxious, if you can get expert advice.
Have the sweat test repeated. I would definitely pay close attention to diet. Food Matters! I've been a respiratory therapist for 23 years and worked in pediatric intensive care for half of that time. If I can be of any support, please just let me know. This is a very difficult and scary time for your family, I'm sure. Many blessings to you and yours.
Copyright 1994-2018MedHelp.All rights reserved. MedHelp is a division of Vitals Consumer Services, LLC.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.