Hi, the hilar nodes being enlarged for more than four weeks can be from three major and totally different types of diseases; chronic infection(TB), immunological(Sarcoidosis), and cancer(Lymphoma). Many different diseases in each type across the whole spectrum, so the only way to narrow it down is through testing(usually histological)combined with clinical presentation(symptoms). Usually the definitive answer comes from testing a biopsied sample of the lymph nodes or if they aren't easily accessible doing a Bronchoscopy with BAL and taking a sample of lung tissue. The hilar and mediastinal nodes are usually directly accessed by doing a Mediastinoscopy. You should also test negative for TB and HIV.
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