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Inerpretation of borderline lab results
Could you please look at the following boderline lab results and see if any conclusion can be drawn about the possible significance? Thanks in advance.
1. 20% fall of 20% at 25 mg/ml in a methicholine challenge test
2. Diffusion capacity of 74% mean; when corrected for
alveolar volume it is 79%, suggesting some loss of lung
volume (VA 4.58)and FVC 101% normal
3. Mild to moderate diffuse bronchial wall thickening
4. Small area of possible interstitial scarring on CT scans
that comes and goes in different places and sometimes
disappears all together
5. elevated IgG level to mold (32.6 with <26 being normal by
Immunocap method); report saying the person has been
sensitized to that mold?
6. Bronchoscopy showing lung inflammation with purulent
secretions?
7. Sputum with a large number of PMNs?
8. Slight flattening of diaphragm on chest XRAy with minimal
interstial scarring (only 1 time)
9. CT scan with minimal vascular congestion
1. 20% fall of 20% at 25 mg/ml in a methicholine challenge test
2. Diffusion capacity of 74% mean; when corrected for
alveolar volume it is 79%, suggesting some loss of lung
volume (VA 4.58)and FVC 101% normal
3. Mild to moderate diffuse bronchial wall thickening
4. Small area of possible interstitial scarring on CT scans
that comes and goes in different places and sometimes
disappears all together
5. elevated IgG level to mold (32.6 with <26 being normal by
Immunocap method); report saying the person has been
sensitized to that mold?
6. Bronchoscopy showing lung inflammation with purulent
secretions?
7. Sputum with a large number of PMNs?
8. Slight flattening of diaphragm on chest XRAy with minimal
interstial scarring (only 1 time)
9. CT scan with minimal vascular congestion
Wildkat: have much in common, I dont know much but my email is
***@****. I'am also trying to fiquire out what is going on, however definately sooner then later, are you going back on prednisone??
***@****. I'am also trying to fiquire out what is going on, however definately sooner then later, are you going back on prednisone??
MEDICAL PROFESSIONAL
There is no significance to the 20% fall of 20% at 25 mg/ml in a methacholine challenge test. Also there is no significance to the diffusion capacity of 74% mean; when corrected for alveolar volume it is 79%, suggesting some loss of lung volume (VA 4.58) and FVC 101% normal.
Mild to moderate diffuse bronchial wall thickening is usually a sign of chronic inflammation. This thickening is probably related to the small area of possible interstitial scarring on CT scans that comes and goes in different places and sometimes disappears all together. The scarring is most likely a reflection of an infectious, non-infectious and/or allergic process, such as allergic bronchopulmonary mycosis (ABPM). The borderline high IgG level to mold of 32.6 (normal <26 by Immunocap method) with the report saying the person has been sensitized to that mold would also suggest ABPM.
Bronchoscopy showing lung inflammation with purulent secretions confirms that there is acute and probably chronic inflammation. The purulent secretions and the sputum with a large number of polymorphonuclear (PMN) white blood cells are highly suggestive of an infectious process. The purulent secretions should have been looked at under a microscope and cultured for bacteria and fungi for clues to find the problem.
The slight flattening of the diaphragm on 1 chest x-ray with minimal interstitial scarring and the CT scan with minimal vascular congestion are of no significance in trying to find the problem. It is somewhat surprising, but encouraging, that the CT scan did not show more of a problem.
Thorough examination and cultures of your purulent secretions may help in finding the problem. If not you will probably require a lung biopsy to find the problem. Whatever is necessary to find the problem should be done now, rather than later. The longer the disease remains active, the more likely irreversible lung damage is to develop.
Mild to moderate diffuse bronchial wall thickening is usually a sign of chronic inflammation. This thickening is probably related to the small area of possible interstitial scarring on CT scans that comes and goes in different places and sometimes disappears all together. The scarring is most likely a reflection of an infectious, non-infectious and/or allergic process, such as allergic bronchopulmonary mycosis (ABPM). The borderline high IgG level to mold of 32.6 (normal <26 by Immunocap method) with the report saying the person has been sensitized to that mold would also suggest ABPM.
Bronchoscopy showing lung inflammation with purulent secretions confirms that there is acute and probably chronic inflammation. The purulent secretions and the sputum with a large number of polymorphonuclear (PMN) white blood cells are highly suggestive of an infectious process. The purulent secretions should have been looked at under a microscope and cultured for bacteria and fungi for clues to find the problem.
The slight flattening of the diaphragm on 1 chest x-ray with minimal interstitial scarring and the CT scan with minimal vascular congestion are of no significance in trying to find the problem. It is somewhat surprising, but encouraging, that the CT scan did not show more of a problem.
Thorough examination and cultures of your purulent secretions may help in finding the problem. If not you will probably require a lung biopsy to find the problem. Whatever is necessary to find the problem should be done now, rather than later. The longer the disease remains active, the more likely irreversible lung damage is to develop.
I just got resultus from my most recent pulmonary function tests.
FEV1 2.10 84%
FVC 2.10 68%
FEV1%FVC 124 % predicted
No measurement of diffusion capacity
It says mild restriction.
What would cause these to vary from one time to another?
I made a mistake in the first sentence. It should say:
a fall in FEV1 of 20% at 25 mg/ml of methacholine and goes on to say is consistent with normal airways hyperresponsiveness.
That was on the test that had a starting FEV1 of 2.47.
One done about 6 months later did not show a drop at all.
a fall in FEV1 of 20% at 25 mg/ml of methacholine and goes on to say is consistent with normal airways hyperresponsiveness.
That was on the test that had a starting FEV1 of 2.47.
One done about 6 months later did not show a drop at all.
FEV1 and FVC of over 100% sounds normal to me. Could be some simple bronchitis, best wait for an expert opinion from the Nj RN.
It would make it easier to interpert if posted your FEV1. This is the amount you can exhale in one second and is the most valuable part of the report!
All of these results are within a few years span and not all the same time. One a couple of years ago showed FEV1 2.48 (92%),
That is when I was having significant symptoms with productive cough, but also while on prednisone. The most recent one was FEV1 was 2.78 (108%)and off prednisone, but still some symtpoms such as shortness of breath and some chest pain.
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