I would like to ask the group if anyone has tried Low Dose Naltrexone for Restless Leg Syndrome. I haven’t taken it myself as my RLS seems under control at the moment - I have done a lot of research and it seems extremely safe and there are many people saying that it has worked extremely well for them.
A little background on LDN (Low dose Naltrexone). Naltrexone is a class of drug known as an opiate antagonist. Its normal use is in treating addiction to opiate drugs such as heroin or morphine. The dose used for this purpose is usually between 50 and 300mg daily. However low dose usage is only 0.5mg to 1.5mg. It is therefore extremely safe and has not been found to be addictive or cause augmentation. The LDN works by briefly blocking the endorphin receptors of the body, usually at night for a few hours. In response the body results in a reactive increase in the production of endorphins, which should result in a reduction of painful symptoms and an increased sense of wellbeing. A lack of endorphins is linked to RLS.
Increased levels of endorphins should be expected to stimulate the immune system, promoting an increase in the number of T lymphocytes. This effect was observed in Dr Bihari's research. This increase in T-cell numbers apparently restores a more normal balance of the T-cells such that the effects of the disease process are significantly reduced.
Low Dose Naltrexone (LDN) may well be the most important therapeutic breakthrough in over fifty years. It provides a new, safe and inexpensive method of medical treatment by mobilizing the natural defenses of one’s own immune system.