I would really appreciate your advice. I have always suffered from frequent bouts of cystitis but 2 months ago came down with a horrible flare that has rendered me bedridden. I have urethral, bladder, pelvic and vulvar pain. It particularly hurts when my bladder is full and when I urinate but I don't so much have urgency and frequency. Finally I was checked and tested positive for ureaplasma urealyticum on DNA swab (clear for absolutely everything else). I took a course of Doxycycline 100mg twice a day for 7 days was retested and it came back negative. I am still continuing to take the Doxycycline and my doctor says I just need to be patient while I heal but the symptoms have worsened. I can't help but think maybe the retest was a false negative (perhaps because I'm still on antibiotics even though was DNA swab) . Should I try taking Clarithromycin? I am desperate and praying this isn't IC.