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Avatar universal

Conclusive?

A year after questionable encounter i took a 30 day course of cipro for prostate. I had been concerned about syphillis due to a chancre one month after exposure and wanted to make sure so I got tested. Tested three months after cipro course (one year and six months after possible exposure). Rpr was negative.  Tested again two months later and again rpr negative. I read that rpr could go non reactive in latent stage so I had fta abs test done.  It was inconclusive and reflexed to the tppa test which was non reactive.  Is this conclusive that I never had syphillis or should I retest due to inconclusive fta abs. I read cipro is ineffective against syphillis bacteria but thought because such a long course maybe it knocked it out and fta and was inconclusive due to treated infection.  Need to let previous partners know.  Should I retest and if so which test?  Or is the non reactive conclusive of never having been infected?
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Avatar universal
Am moving on.  I was referring to the symptoms that you mentioned.  The rash, arthritis and fever and thought you were saying that would be a reason to reconsider syphilis and to talk to my doctor.  I now understand it as meaning those would be signs of a different infection other than syohillis.  Sorry for the confusion.  
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Avatar universal
Am going to move on. My confusion was in that I thought the symptoms you listed(rash, arthritis, and fever) were in reference to syphillis but see now that you meant those symptoms might be something else such as lupus. Which then in turn I should talk to my doctor about something other than syphillis.  Thank you again.  
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239123 tn?1267647614
MEDICAL PROFESSIONAL
None of these symptoms is the sort that would raise concerns about an autoimmune condition.  I should have thought to say that in my last comment.

Thanks for the thanks.  Time to move on, though.
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Avatar universal
Sorry. I was going off the talk to your doctor part thinking you meant possible infection due to other symptoms and based off of light positive. I take you meant talk to doctor about possible other infections.  Is this correct and I really appreciate your advice?
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239123 tn?1267647614
MEDICAL PROFESSIONAL
These symptoms do not change my opinion or advice.  Your anxieties are affecting your objectivity, which appears to be more or less absent on this topic.  Why are you working so hard to convince yourself (and me) that you have some sort of atypical case of syphilis?  You're just going to have to accept the apparently difficult news (and scientific evidence) that you do not.  I will not discuss it further.  This thread is over.
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Avatar universal
I did have jock itch and balanitis last summer.  Both were around at the same time and both went away with anti fungal.  Also have been having irritation at tip of penis and a case of epididymitis but I also had a vasectomy almost two years ago.  That's why I am concerned about the inconclusive test.  I know tppa is non reactive but thought I should get a tie breaker because of other symptoms.  I am also concerned because my wife had sores in her mouth a few months ago and was diagnosed with coxsackie. Should I be concerned?  And should I get another fta abs?   I have tested negative for all other stds.  
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239123 tn?1267647614
MEDICAL PROFESSIONAL
Weakly false positive FTA-ABS test results occur occasionally, without explanation.  You are correct about it being a demanding test to perform correctly.

In rare cases, a false positive FTA-ABS can result from certain autoimmune diseases, like lupus.  Assuming you are outwardly healthy, this isn't anything to worry about.  But if you ever have unexplain skin rash, arthriits, fever without obvious origin, or are otherwise unwell, this would be something to discuss with your doctor.
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Avatar universal
Thank you so much for the pep ace of mind.  My urologist was of the opinion that three days of cup to would have been enough which was contrary to what I have read.  Thank you for your expert advice.  Would you have any insight as to why fta abs would be inconclusive?  I know it is a difficult test to perform and is highly subjective.  
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239123 tn?1267647614
MEDICAL PROFESSIONAL
Welcome to the forum.

Ciprofloxacin and all related drugs (the fluroquinolones) are entirely inactive against syphilis.  No matter how long the treatment, cipro has no effect at all.  On the other hand, it doesn't matter, since your test results prove without doubt you do not have syphilis and never did. Something else caused the sore that you thought might be a chancre.  You do not need to say anything about syphilis to any sex partners, past or future.  And you definitely do not need any more testing for syphilis.  Forget it and move on.

Best wishes---  HHH, MD
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