Welcome to the forum. Thanks for this interesting question.
You had an exposure that could well have been high risk, especially since you apparently do not have HSV-1 (based on the negative blood test). (If that test had been positive, it would mean you were infected in the past and are now immune to a new HSV-1 infection.)
While I understand the attempt to prevent infection by prescribing valacyclovir (Valtrex), such treatment after exposure does not prevent HSV transmission. In animal experiments, to be effective in prevention the drug has to be in the system before exposure, or given within 1 hour. However, it is possible such treatment could delay symptoms and/or positive test results.
Having said all that, absence of symptoms at 24 days is reassuring. Had you been infected, then even with the valacyclovir treatment, I would have expected symptoms by that time. However, I cannot say for sure and would encourage you to continue to be on the lookout for both genital and oral symptoms; and to have a follow-up blood test. To your specific questions:
1) Valacyclovir delay of symptoms: see above.
2) The longer you go without symptoms, the greater the chance you were not infected.
3) Yes, this might happen. While an 8 week test makes sense, I would also recommend a final test after 3-4 months. If that is negative, you can consider yourself home free.
4) This isn't really known. Most people who are alarmed and on the lookout for even mild symptoms probably would notice something. But not all.
5) Oral infection alone would be most likely, since HSV-1 more readily infects oral tissues more than genital. But infection of both exposed sites certainly could occur.
6) I'm not sure why this would be on your mind. Having HSV of either type does not interfere with response to any vaccines at all.
In summary, the odds are very strong (90% or higher, as a guess) that you were not infected. But do follow through with the additional blood tests to be certain.
Best wishes-- HHH, MD
You continue to overreact unnecessarily, and you can't expect another round of hand-holding every time you have another anxious thought. This information doesn't change my opinion or advice. And even if you were to have acquired either oral or genital HSV-1, it shouldn't be any big deal (
http://www.medhelp.org/posts/STDs/Recently-diagnosed-with-Genital-Herpes-HSV1/show/969931). But I continue to believe you were not infeted.
That will end this thread. Try to move on without worry.
Hello Dr. H,
I forgot to mention that last week i had a mild elevated temperature in the nights ( at around 99.5 ) but it would be around normal during the day and later when i would go to sleep. Would this temperature along with the bothersome sensation in my rigth thigh be the symptoms of an atypical outbreak or is it my anxiety?
Thank very much, i have been dying of anxiety for the last three weeks
Three weeks is said to be the maximum, and I've never had a patient with new HSV whose incubation period was longer than 10 days. But I don't know that I've ever had a patient who had taken anti-herpetic therapy after exposure. As I said, it is doubtful you were infected, but I would not guarantee it until you have had a negative blood test after 3-4 months.
Thank you very much Dr H.
Yes, the cold sore was healing. Just one quick follow up. What have been the latest you have seen a primary outbreak to ocurr after exposure ( if there is to be one).
This is my final coment. Thank you very much for the help.
Thank you very much Dr H.
Yes, the cold sore was healing. Just one quick follow up. What have been the latest you have seen a primary outbreak to ocurr after exposure ( if there is to be one).
This is my final coment. Thank you very much for the help.
I should have added that your partner's oral herpes seems to have been healing, as indicated by the scab, and there's a good chance it was not infectious at the time of exposure.