This expert forum is not accepting new questions. Please post your question in one of our medical support communities.
Avatar universal

HSV 2 Test Results

I will try and keep this short.  I am a male in my mid-twenties, healthy.  I had been dating my GF for about 6 months (having unprotected sex) when we both decided to get tested  in June last year. I came back HSV 2 positive (Type I: 0.29 Type II: 2.19, believe it was HerpeSelect).  She came back negative for both.   I have not have or can remember any symptoms in the past.  After discussion. we decided together that we would continue our sex life (2-3 times a week, sometimes more), and continued to have unprotected sex.  Approximately a year later, with no symptoms (I was very attentive to any changes/conditions in gential region) I got a Herpeselect test again to confirm first test result:  HSVI: Negative (didn't get a exact number), HSVII: 1.93.  She was again negative for both.  Question:

1.  I have assumed all along that I have HSV2, but my numbers are in the potential false positive range (1.0-3.5).  What are the chances of two false positive results?

2.  Is it possible to have no initial or reoccuring outbreaks but have asymptomatic shedding?

3. What causes false positives?

4.  Would you recommend a WB test to definitely confirm results?  Is it worth it?  

Thanks a lot for all the info.

Read more
Discussion is closed
Upvote - 0
1 Answers
Page 1 of 1
239123 tn?1267651214
I'll go straight to your questions.

1) Most false positives occur in people with positive HSV-1 results.  In people without HSV-1 antibody, any HSV-2 result above 1.1 is true positive.  You are infected with HSV-2.

2) Yes, indeed.  You should assume you have periods of asymptomatic shedding of HSV-2, regardless of having never had symptoms.

3) The biological and/or technological reasons for false positive HSV-2 results are not fully understood, certainly not by me.  But this is irrelevant to your situation.

4) There is no reason for Western blot.

Best wishes--- HHH, MD
Discussion is closed