Yes, it could mask symptoms.
I answered your other question above and said you could retest 3 days after stopping therapy. EWH
Thank you for your response. I honestly can't remember if I started the PenVK the evening before or the evening after the event. I was having tooth pain related to an upcoming removal of a wisdom tooth and they gave me the antibiotic to help. Regardless, if there was a gonnorhea infection (small chance I understand) would the antibiotic mask symptoms? If so, after stopping the antibiotic, would symptoms appear and if so in what time period? The standard 2-5 days after? I apologize for nitpicking.
Welcome to our Forum. I'll be happy to comment. If you were on PenVK at the time of exposure, since more than half of gonococci in most settings are susceptible to penicillin, your risk for infection with gonorrhea from this exposure is, if anything, lower than if you were not taking the penicillin. If anything, the penicillin might also reduce your risk for NGU as well although this is, admittedly, a guess since there are no data to answer this question.
If there are no symptoms, I really see no reason for testing however, if you choose to do so, I would suggest that you wait at least three days after your last dose to seek testing to make sure that all penicillin is out of your system and to allow tests to become positive (which I doubt will happen).
I hope this comment is helpful. EWH