This information makes it seem like a reaction to the drug, perhaps contact dermatitis. You may be allergic to docosanol or one of the other ingredients in the cream. But this is only an educated guess; I cannot make a specific diagnosis.
Thanks for the input Doc. I forgot to mention that the new symptoms following the abreva application took place in two spots, both of which were the exact locations where I applied the abreva most heavily (e.g. Not just on the herpes blisters but on the entire surrounding area). Wouldn't that seem to be too much of a coincidence to be an additional herpes outbreak, especially given that the following day the new symptoms occured whereas additional sores did not present for the entire first week of the outbreak? Thanks again!
Welcome to the forum.
Abreva (the trade name for docosanol) is not highly effective against HSV and has never been studied for genital herpes, only oral; and even there is barely better than placebo, if at all, and is not recommended by any authoritative agency for herpes treatment. Accordingly, I have no personal experience with docosanol and no familiarity with its side effects; I cannot comment on whether you are having drug-related irritation, a continuing herpes outbreak, or something else entirely. However, recurrent herpes outbreaks almost always start to heal within 10 days and are completely healed by 2 weeks, and new lesions rarely keep appearing beyond the first 2-3 days. (New lesions can continue to appear for up to 2-3 weeks in initial genital herpes, but not with recurrent outbreaks.) That suggests that a continuing herpes outbreak is unlikely. To my knowledge, docosanol would not prolong an outbreak or somehow cause new lesions to appear.
For what it is worth, your description of the outbreak before treatment is not typical for genital herpes. If previously you have had similar episodes confirmed as herpes, then presumably that is what you have. But if this is a self-diagnosis that has not been professionally confirmed, I recommend you see a knowledgeable provider for diagnosis.
At this point, my advice is to stop docosanol (which you may have already done). Things should heal up promptly, regardless of the cause. If that doesn't happen, see a doctor or clinic for professional evaluation.
Good luck-- HHH, MD