DR. H. Please confirm my understanding on the RPR and TPPA testing process. My boyfriend tested false positive for RPR (he has in the past as well, due to complications from a childhood disease - mono), but tested negative to TPPA as in previous experiences. Does this confirm that he does not have syphilis? Do I need to get tested to reconfirm? I only ask since I have experienced symptoms which may be identified as syphilis ie. mouth sores, sore throat, small areas of discoloration on my arms that look like razor burns (but disappeared in about two days). I have not been with anyone else. His titer to the false positive on the RPR was 1:2, which in itself is borderline for negative, as negative is based on < 1:1. Please advise. Thank you
I am not an expert by any means, but it is my understanding that a TPPA test does not have many false negatives. It does have some amount of false positives. Furthermore, the TPPA generally stays positive even after treatment.
My assumption is that a positive RPR and a negative TPPA means that the true result is negative.
The reason why I was concerned is somewhere on this thread you had mentioned false negative "prozone", I beleive. Does this only apply to RPR? What else can cause sore throat with white patches, mouth sores and general feeling of malady? Also, these spontaneous rash-like skin condition is troublesome. I have been losing weight also. Please advise. Thank you
There is no prozone for TPPA; a negative is a negative.
There are hundreds of things that cause rash and the other symtpoms you describe for your partner, and for your weight loss, that are more common than syphilis. I can't even guess. But it definitely isn't syphilis. See a health care provider.
Copyright 1994-2018MedHelp.All rights reserved. MedHelp is a division of Vitals Consumer Services, LLC.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.