dear sir:
On Nov 10, I had a sexal intercourse(Condom & French kiss) with a syphilis patients(Trust 1:8; TPPA 1:320). One week after the contact(Nov 17), my serological tests were Trust negative, TPPA negative.
At the same day(Nov 17),I received the epidemiologic treatment. I have received 2.4 million units of Benzathin
Penicillin once a week, interval one week, total 4 injections. Because I was worry about TP penetrate into my CSF,I received oral Doxycycline 200 mg one time, two times a
day, maintained 15 days.(Nov 17-Dec 3)
I have finished my treatment on Dec 14 and I repeated my serological test on Dec 14 (5 weeks after contact). The
result were Trust negative ; TPPA negative.
Now my questions are (I have asked you same similar questions, but I am facing a medical examination in the
next month for entering a company. I holp you can forgive me )
(1) Is there any possible that my TPPA will turn positive in the future ? (I am so worry about the TPPA, because the physical examinztion includes TPPA test)
(2) Is there any possible that some TP still hide in my CSF now ?
(3) Should I need other treatment or test? If I need, what should we do?
(4) I have read some paper during this period. Some make me ease, but others make me anxious. Most paper about epidemiology (such as MOORE, Epidemiologic Treatment of Contacts to Infectious Syphilis and yours Azithromycin Compared with Penicillin G Benzathine for Treatment of Incubating Syphilis.etc) report that epidemiologic treatment with Benzathin Penicillin are 100% effective. However, others report some patients or
rabbits received preventive treatment on seronegative stage but TPHA or FTA-abs turn positive at last. (Eg:J.LESInISKI, Specificity, sensitivity, and diagnostic value of the TPHA test)
Those papers make me confuse. If you convenience, would you give me some explanation or offer me some paper which include the answers
Thanks for your help