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adenoviral urethritis?

Hi,
I am a 38 year old male. For the past 3 weeks I have been having a burning sensation in the urethraand difficulty urinating (blocked sensation when I start urinating) which really bothers me, I also have frequent urination. No fever or discharge. At one point I also had a high count of lymphocytes in the urine, but checking again the count is normal.
I have tested three times negative for bacterial infection in urine, negative for full panel STD PCR, and doctor checked and said that my prostate is not enlarged....
Reading some posts and in PUBMED, I think that I may have a adenoviral urethritis. Also, a couple of weeks before symptoms began, my 3 year old son had pink eye, and my wife had a throat infection. My wife and I have occasional oral sex, so I am thinking that this may be how I was infected.
The caveat is, that when I am treated with cypro (on my second 10 day treatment now), I feel better (less burning sensation and symptoms) which to my understanding does not agree with adenoviral infection.
I am worried, because this has been going on for three weeks.
I would very much appreciate knowing what is recommended and what you think.
Is there a test to verify or discard the adenoviral infection option?
Does the reduction is symprtoms with cypro indicate a bacterial infection that was false negative in culture? And if so why did it not resolve after the first 10 days of cypro?
What are the possible complications?
What can be done to treat/alleviate adenoviral infection and how long does it usually last?
Thanks very much!!
5 Responses
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300980 tn?1194929400
MEDICAL PROFESSIONAL
I do not have the advantage of examining you and things are clouded by having taken antibiotics which, while apparently helping are being given in the absence of any proven infection.  I would not have one this to start with but what has been done is done.  

You indicate that you have negative STD tests and a negative evaluation for prostatitis.  If I were you, I would finish the course of antibiotics you are taking and then stop. If your symptoms return, I would go back to the doctor who has evaluated you an get re-tested.  I woul not confuse things by seeing another doctor who has not seen you in the past.  

EWH
Helpful - 0
Avatar universal
Hi Doctor, thanks so much for your additional answer.

Based on your answer, I understand that you think STD, adenovirus and prostatitis are not the case (you are ruling out prostatitis because of the negative urine test following the rectal exam?).

In that case, to my understanding the only remaining option is urethritis, and given that it is responding the cipro and therefore is probably bacterial (?) then how could the urine cultures be coming back negative....?

I must say that I am confused.

Not sure that I understand your last remark, I didn't have any exposure that I regret, and I am certainly not imagining the burning sensation and pain that I am experiencing, nor the significant improvement when I take cipro.

Would appreciate your recommendation on what to do next.
Helpful - 0
300980 tn?1194929400
MEDICAL PROFESSIONAL
Taking the penicillin was a dumb thing to do but it probably not influence your test results.  I see no need to re-test when yo finish your cipro.  since you are taking the cipro and it seems to be helping, you should finish it.  When you do, I see no need to re-test.

Your understanding of adenovirus is oncorrect.  Adenovirus urethritis does not result from direct inoculation into the urethra.  As I said early adenovirus is self-limited and does not last three weeks.  Why re-test for something you can do nothing about but allow it to run its course.

sounds like prostatitis has been ruled out.

Having your urethral meatus stuck together in the morning would not cause the sorts of symptoms you describe.

Finally, I should point out that sometimes after an exposure that, in retrospect, one wishes they had not had, persons tend to examine themselves and be far more attuned to genital sensations than in periods when they are not concerned.  This in turn leads to noticing what turn out to be normal sensations that might have been not noticed or ignored at other times.  Perhaps this was a contributor to your situation.  EWH
Helpful - 0
Avatar universal

Hi Dr. Hook, thanks very much for the answer.

Yes, I have been seeing my family doctor, and I suppose that the next step is going to see a urologist?

The night before I gave urine for the STD PCR I took one pill of Penicillin V that my wife was taking for her throat infection (probably Strep). Since this is a PCR test, how could taking an antibiotic result in a false negative test? Also I have no excretion, which I thought was symptomatic of STDs. Lastly, I am sure that my wife does not have an STD and in any case I use a condom and have had no other partners, so where would I get an STD?
That said, and I look forward to your answer. Would you say that I when I finish the current regimen of Cipro and if I still have symptoms, I should retake the urine STD PCR test?

Regarding adenovirus, my very limited understanding from the forum was that this can be transmitted from oral sex and fit in well with my wife having a sore throat. But as you say I did not have a sore throat or conjunctivitis myself. Is there any way of ruling adenovirus  out?

Moving to Proststitis.  The only pain that I have is in the urethra, mainly at the inside base of the penis. No pelvic pain or other. As I mentioned the doctor gave me a rectal exam saying the there is no enlarged prostate and a urine test for bacteria immediately after, which was negative. Still, assuming that this is prostatitis, I understand that the treatment is a long regimen of antibiotics. Correct? How can bacterial prostatitis be diagnosed? Is non-bacterial prostatitis common? And how can it be diagnosed and treated?

Another  point, I had experienced once or twice a situation where in the morning the urinary miatus was 'glued' closed by semen after having sex previously. Therefore when I went to urinate I experienced urine pressure for a moment before mechanically opening the meatus. Would this cause the symptoms that I am experiencing?  Is it possible that there was backflow of urine into the prostate? Would this cause mechanical or bacterial infection and how would it be diagnosed and treated?

As the symptoms have been going on for a while, this is disputing my life, not to mention the fact that I am not having sex for fear of pain and worsening the situation (although it may be worth mentioning that after the symptoms began on one occasion I did masturbate and the semen was yellowish, after which I experienced temporary reduction of symptoms).

Sorry for the multiple questions, would very much appreciate your answers. Thank you!
Helpful - 0
300980 tn?1194929400
MEDICAL PROFESSIONAL
Welcome to our Forum.  I'll try to help.  Were you taking cipro at the time of your STD tests?  If not, you should believe your tests which have ruled out STD.  On the other hand if you were taking the cipro, this could lead to a false negative test.

Another question- have you been seen by a doctor or are you pursuing this on your own?  

My guess is that your problem is not an STD. Adenovirus does occasionally cause urethritis but in adenovirus infection, urethritis is just one of several manifestations of systemic adenovirus with the other symptoms being conjunctivitis or sore throat.  This infection is transmitted through activities of normal living- on the hands, through non-sexual touching and even by kissing. It is not an STD in the traditional sense.  My guess however is that this is not adenovirus- it is relatively uncommon, typically resolves in less than a week, and does not respond to antibiotics.

On the other hand. prostatitis seems like a possibility which should be considered.  Your symptoms are more consistent with this and this problem would respond, at least temporarily, to antibiotics like cipro.

Hope these comments are helpful.  When you answer my questions I may have more comments.   EWH
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