This is not a question, but a comment. My husband has been on Xyrem since the fall of 2005. He now has a considerable amount of central sleep apnea and is being removed from Xyrem to prove that the apnea is indeed coming from the drug. He was diagnosed with narcolepsy, but I have never been real convinced of that because he has always been sleep deprived and depressed. The depression he would not admit until just the last year, and with him it is an "off-limits" subject. Now that he is on Medicare, the cost for the Provigil and Xyrem is more than a major house payment. Patients really need to be counseled to give a drug or any therapy a sincere trial because I believe if some patients don't see quick results, they give up on a drug that may be helpful. Xyrem should be a very last resort.