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Hormonal Problems

A 15 year old boy's thyroid is down, his cortisone levels low, his testosterone levels low and his growth hormone levels high. Taps of his knee removed up to 500 cc of fluid, but no evidence of anything specifically wrong inside the knee, just that it was being damaged. He looked gaunt and unhealthy.
1. what hormonal problem could be causing these symptoms?
2. Why would joint damage be associated with rapid growth and low testosterone levels?
2 Responses
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523918 tn?1244549831
You should go to a pediatric endocrinology, this boy need to do much more tests like  Insulin-like growth factor 1 (IGF-1) , LH, free testosterone,  ACTH, etc. and physical examination (signs of puberty, growth, thyroid, etc)  He needs treatment. GH is made by the pituitary gland and is needed for growth, so if he is 15 years old, is he growing to fast?? (explains knee problem) is there any signs of puberty? I would post in the pediatic endocrinology expert forum, Dr D. Guy is very good answering this kind of problems.
Helpful - 0
499534 tn?1328704178
This would be a great question for Dr Lupo at the expert thyroid forum. You can find it toward the bottom rt side of this page under expert forum....just click on thyroid.
There seems to be a lot involved here with the endocrine system. Sometimes you will see a combination of Thyroid disfunction and Adrenal disfunction....they actually go hand in hand quite often. Addisons is the name of low adrenals causing low cortisol.
Possibly even the pituitary is involved? Has anyone run PTH bloodwork along with all the other tests?
Let us know what you find out. :)
Helpful - 0
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