Dear Dr. Lupo
Could you answer this post (RJ1221 asked me to try to post her question):
By RJ1221
Feb 05, 2009 11:47AM
My daughter who is Congenital Hypothyroid is now 2 and half year old has following readings:
FT4 - 26.48pmol/L ( Range - 11.5 - 22.7)
TSH - 7.60 mclu/ml ( Range - 0.7 - 6.4)
The last times reading was also with higher TSH - 14.51mclu/ml and FT4 - 20.40 pmol/L. The dosage was increased slightly and after 6 weeks I got the above stated readings. Most of the times I keep noticing this pattern , as on increasing the dosage the FT4 increases and though the TSH reduces better than previous time, but still higher on the normal range.
What can be the reason , I gathered about "if it is then consider thyroid hormone resistance or a TSH pituitary tumor -- both VERY VERY RARE." from this site.
Please find the below history of her reports if that can help further.
1 Year 5 25-Dec-07 1.53 0.8 - 2.3 ng/dL 4.77 0.7 - 5.7 ulU/mL
1 Year 7 19-Feb-08 1.6 0.8 - 2.3 ng/dL 12.85 0.7 - 5.7 ulU/mL
1 Y 10 M 13-May-08 24.49 11.5 - 22.7 pmol/L 2.98 0.7 - 6.4 mclU/ml
1 Y 11 M 26-Jun-08 28.57 11.5 - 22.7 pmol/L 2.53 0.7 - 6.4 mclU/ml
2 Y 1 M 20-Aug-08 25.19 11.5 - 22.7 pmol/L 4.49 0.7 - 6.4 mclU/ml
2 Y 5 M 16-Dec-08 20.4 11.5 - 22.7 pmol/L 14.51 0.7 - 6.4 mclU/ml
2 Y 6 M 4-Feb-09 26.48 11.5 - 22.7 pmol/L 7.6 0.7 - 6.4 mclU/ml
I am unable to post my query onto that expert forum as it always says that the limit of submissions are done for the day.