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Thyroid Cancer / Nodules & Hyperthyroidism Forum
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Hypothyroid symptoms adrenal symptoms TPO antibodies

Hi, I've always suspected I have hypothyroidism due to years of the usual symptoms, but my TSH is always "normal".  I have been reading everything I can about thyroid problems for years.  Well, I finally had my FT3, FT4 and antibodies tested in June, 2013:

TSH:  1.02, (range:  0.34-5.60)  
FT3: 3.0, (range:  2.3-4.2)
FT4:  0.72, (range:  0.58-1.64)
TPO Ab:  98, (range: 0-34)
TG Ab:  <20, (range:  0-40)

I also have elevated liver enzymes.  AST:  95, (range: 4-44), ALT:  150, (range: 5-40)
And I had a SPEP done due to elevated globulin and it came back showing elevated gamma globulins (polyclonal gammopathy).
I have a fast pulse, over 100, and heart palpitations (strange because hypo usually causes SLOW pulse).  I was prescribed Metoprolol.  It brought my pulse down into the 80's.
Here's where it gets really strange:  I had some red patches on my shoulders and was prescribed Clotrimazole-Betamethasone cream for it.  When I started using the cream I immediately noticed a COMPLETE ELIMINATION of some of my symptoms:  For the first time in my life I was falling asleep and waking up early without an alarm, and only sleeping 7 hours a night instead of 10-12!  My blood sugar stopped crashing and I didn't have to eat every few hours,  my pulse came down into the low 60's and the HIVES I normally experience several times a day disappeared!
I'm  guessing this happened because of the corticosteroid in the cream.  Could this mean I have a cortisol problem?  Adrenals?  Pituitary?  Or could it be something else?  I don't have any diagnosis yet.  Thanks!  
1 Responses
97953 tn?1440868992
MEDICAL PROFESSIONAL
It is very common to have normal thyroid function with positive TPO-ab's.  Your symptoms are not likely thyroid.  Topical betamethasone should have little systemic effect, but you could explore the adrenal function with your doctor to confirm.
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