I have been taking Synthroid .075 daily for years and I feel it helps considerably. Before I started taking it I was depressed, tired, and found it hard to concentrate on my university studies. I have been gaining weight for years though despite eating properly (truthfully, as guided by a dietician). I was recently diagnosed with PCOS and (Gen) Metformin was prescribed. I began having severe upper thigh pain in my left leg within days of starting Metformin which subsided when I stopped the medication, and started again when I resumed. Pain to the point of using crutches where I have NO pain otherwise. Yet, the doctors are saying this pain is not a side effect of Metformin. I want this medication to work. Have you heard of such side effects?
Also, I take my Synthriod at night before bed. Is this advisable or is there a "prime time" to take it?
Thank you very much,