I am a 38 yo female diagnosed in November with hypothyroidism (TSH 7.85) following YEARS of difficulty losing weight (I'm about 20 lbs overweight) and fatigue. I have blood tests dating back to 1992, and my TSH was always in the over 3 range. I started on .05 synthroid, my TSH decreased to 2.22, but my symptoms didn't really improve (with the exception of brain fog, which had developed in September). Increased to alternating .05 and .075 late January, most recent TSH was 1.48. Meanwhile, my blood pressure (usually normal) has gone up (130/90) and my resting cholesterol has gone from 184 in August to 235. I've also noticed some swelling, particularly in my hands (difficulty with getting rings on and off). I talked to my MD about Armour, but he doesn't think the scientific evidence for a trial is compelling. I guess I have a few questions. Should I be seeing more of an alleviation of symptoms by this point? (.05 was started 11/30). I work out (cardiokickboxing and weights) 4x week for an hour (for over a year now) and watch what I eat. Second, could the increase in BP, swelling, and/or cholesterol be related to the thyroid? And third, should I push on adding Cytomel or Armour to my regimen? Thank you in advance for any help you can provide.