Thyroid Cancer / Nodules & Hyperthyroidism Forum
This expert forum is not accepting new questions. Please post your question in one of our medical support communities.
Avatar universal

Thyroid issues still or insulin resistance?

Dr. Lupo:
Thanks for your answer to my earlier question.  I have hypothyroidism and I have also been diagnosed with PCOS using labs and ultrasound on ovaries.  I am still experiencing horrible fatigue and occasional tingling in my hands and feet.  I had thought this was thyroid-related, but now I am wondering about insulin resistance.  I am concerned since I have PCOS as well as relatives with type 2 diabetes.  I asked my doctor about it and he said that my fasting-glucose levels have always been normal (in June it was 81), my non-fasting serum insulin was normal (level was 8), non-fasting c-peptide was normal (level was 2.9), so it isn’t an issue.  I requested the 2hr GTT w/insulin check.  He felt it was a waste of my time to get this test, but gave me the order to get it done anyway.  I did that yesterday.  
1) What would indicate insulin resistance with this test?  I am considering switching doctors because I am not sure if the doc I am seeing is right for me.  
2) Would a reproductive endocrinologist treat both PCOS and hypothyroidism or do they only treat people with issues in trying to get pregnant?  
3) I have heard of many people with PCOS taking Glucophage.  If this is a proper treatment for IR, is the extended release version better than the regular?

Thanks for your help.

Most recent labs:
November (while on .88mcg Synthroid, 10mcg Cytomel, 200mg Prometrium 18days/mo)
Free T4 1.2 (.8-1.8)
Free T3 325 (230-420)
TSH  .22 (.4-4.50)
TPO AB 411
1 Responses
97953 tn?1440868992
1 - testing so far is not diagnostic of insulin resistance, but PCOS is an insulin resistance syndrome, so the basic tests may be normal in early disease

2 - depends on the doc, some would treat both

3 - this can be done, the ER version decreases stomach side effects.  I am not as up to date with the role of glucophage in PCOS, but is is a common approach.  Diet/exercise is the best approach.

Thyroid levels look ok, no room to increase the doses though.
Didn't find the answer you were looking for?
Ask a question
Popular Resources
We tapped the CDC for information on what you need to know about radiation exposure
Endocrinologist Mark Lupo, MD, answers 10 questions about thyroid disorders and how to treat them
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Here’s how your baby’s growing in your body each week.
These common ADD/ADHD myths could already be hurting your child
This article will tell you more about strength training at home, giving you some options that require little to no equipment.