8mm is still small - the risk of cancer for "indeterminate" varies by the cytopathologist (may be 10-50% risk - average is 20% usually).
Afirma depends on this risk of cancer question - ie, the negative predictive value of the test is higher if the risk of indeterminate being cancer is lower. This is very complicated statistics but for a small nodule like this, assuming no other susicious ultrasound features a "benign" Afirma test would favor observation. Would consider a second opinion from an endocrinologist who does his/her own ultrasound to review the situation with you.
I just found out I spelled the Affirma test wrong!
Also, I forgot to mention that my isthmus orginally described as almost all cystic for about 6 years,I hadn't had an ultrasound since May 2010 until January of this year because the nodules were stable and the one on the left,the largest 1cm which I think is only a little bigger now,was the only one that was mostly solid. But now this isthmus nodule is mixed cystic and solid and the solid part is what grew,it's always been hypoechoic,and none were described as hypervascular before,until in January the isthmus nodule that grew 50% now is described as midly hypervascular.
My post was too long so I have to post the rest.
The pathologist and the Dr.who just did my FNA told me that my nodule is classified as a indeteriminate follicular neoplasm with oncocytic features! My isthmus nodule was the only one biopsed this time because it grew 50% in almost 3 years. I just turned 48 April 1,how likely is to be Hurthle or follicular cancer? And how accurate is the FERMA test? I was told today by both the pathologist and the doctor who did my recent FNA that I have a 20% chance of cancer now.I'm obviously very scared now. You had reassured me and others on here that Hurthle cells are a common benign FNA finding,and that it's only a concern when you have 75% or more,little or no colloid and lympocytes.
If you could please answer when you can,I really would appreciate it.
Thank You.