thyroid nodules bloodwork normal

[L777]

I have every symptom of hypo - most concerning weight gain and hairloss - but all they symptoms over the last 8 years or so - docs have said thyroid enlarged - bloodwork always normal - finally at my last annual exam - new doc said "time to figure this out" -
throid atoantibodies <20, throid peroxidase 19, TSI 113, t-3 uptake 31, t-4 free 1.0, t-4 7.9 and free t4 2.4, and tsh .94
had sonogram - multi cystic nodules  and 2 cold nodules 1.9cm on rt and 1.5 cm on left - scheduled for apt with ENT for possible FNA on July 10.. worried as thyroid enlarged for last 8 - 10 years and gradual symptoms..

My question - would the above cause hypothyroid symptoms?  or am I crazy -
should I be concerned?  Will it get worse?  What treatment plan would be advised? - just advise, I will seek 2nd opinion as well - I try to take responsiblity for my health and educate myself.

[lisseree]

My multinodular goiter is acting up, and with it I'm experiencing hair loss and weight gain and dry skin and sleepiness (among other things.) BUT, my labs came back normal too, so don't feel alone. My goiter has just grown over the years too, and only now seems to be pressing on surrounding neck structures and causing problems.

I just firmly believe that it's too coincidental that all this goiter business would happen at the same time as hair loss, weight gain, fatigue, etc, but that they can't tie them together due to the fact that the labs are normal. Am I making sense? I'd almost bet my left leg that if they remove my ailing, growing, throbbing thyroid gland, that those other "hypo-like" symptoms would go away too when my meds got regulated. I'll be my own case study and share the results.

[Mark Lupo, M.D.]

The nodules will not cause symptoms (other than throat pressure, hoarseness, etc) unless the thyroid function is altered.  You list normal thyroid labs, including antibodies - so the weight gain and hair loss are not likely thyroid related.  

The dominant nodules need to be biopsied -- best under ultrasound guidance given that you have a multinodular gland.  Only 5-10% of nodules represent cancer, so likely this is a benign process that can be monitored unless you have pressure symptoms from the nodules.

[kitcurious]

I am sorry about the nodules. I know little about this except that your TSH is like, perfect. Wish I had it. Usually the worse the TSH is the worse people feel.
Look forward to doc's respone.

[kitcurious]

Also, if they gave you a Synthroid med, it would probably make you hyper thyroid since your levels are so low now. It's not hypo...have you ever tested hyper ?