Could there be a connection between cortisol dysregulation and chest pain?

[Shiela747]

I am a female age 54, being tested by neurologist for Myasthenia Gravis with possible associated disease. Positive EMG, positive clinical assessment, sero-negative. Insomniac for 15 months when symptoms emerged. Prior to that had a nontoxic cold nodule. When I awake, in the morning and every time I awake during the night, I awake to medically confirmed non-cardiac, non-musculoskeletal chest pain. Pain seems to be consistently related to sleep/wake mechanism only. Lasts maybe 5 minutes after waking, feels like a tightening or spasm. I've read that cortisol weakens the activity of the immune system. Could the hypothalamus be giving orders to the adrenals to produce a super-surge of cortisol in response to Myasthenia Gravis or other associated disease, in an effort to control the overactive immune system? I couldn't find a forum to address this so I hope someone will refer me to the proper forum. Thanks.

[Shiela747]

Is there a cortisol test that will measure spikes during the night/day?

[Mark Lupo, M.D.]

Would discuss with your neurologist.  If there is an adrenal question, then blood tests for cortisol can be done to ensure adequate adrenal function.