When my dose was increased from 112 to 125 mcg, I gained 14 pounds in a short amount of time. I had horrible headaches on levo (125), so I switched to Synthroid. I started running and have lost 17 pounds. I now have brief heart palpitations when I exercise hard. I say brief, since I immediately start walking. I also have horribly long and heavy periods. My last TSH test was 2.485. My doctor said I could go back to 112, in case I am over-medicated, but my numbers are good. What should I do? I thought I could go back to 112, since I was less hungry at that level and less weight, but I read heart palps may also be a sign I am still under-medicated. Any advice would be greatly appreciated!