Multiple endocrinological neoplasia and MTC

[Tess55]

I have primary hyperparathyroidism.  I was in an accident and a left adrenal mass was noted on my C.T. scan of the abd.  It measures 2cm X 2 cm.  I advised my endocrinologist of this finding and he told me I have a hereditary condition called M.E.N.  (Multiple endocrinological neoplasia).  It does not appear that I have a pheochromocytoma but the ultra sound of my thryroid showed bilateral hypoechoic, non vascular nodules.  On on the right and 3 on the left.  My question is does  MTC occur 100% with M.E.N?  I cannot find a site that speaks specific to my question.  Thank you.

[val1198]

I had a parathyroid adenoma removed and now have primary aldosteronism.  I had a MEN1 genetic test and the result was negative.

[rach118]

Hi I have MENS and had my thyroid, parathyroid and lymph nodes removed because of MTC.  Have your calcitonin levels been checked?  I have done a lot of research on it and if appears the only way to prevent the MTC from occuring is to remove the thyroid.  I'm not a Dr however I researched it a lot because of having it.

[Mark Lupo, M.D.]

One cannot conclude that a patient with primary hyperpara and an incidental adrenal adenoma has MEN.  Certainly testing for pheo needs to be done.  Blood tests for calcitonin as well as neck ultrasound can help screen for a thyroid nodule - which you appear to have.  FNA biopsy should be done.  MTC is not 100% w/ MEN.
www.endocrineweb.com may be a useful site.