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Still lethargic after Silent Thyroiditis treatment - Why?

I was diagnosed August 1, 2010 with silent thyroiditis.

My stats are (Range: TSH 0.40 - 4.50 // Free T4 0.8 - 1.8)

08/01/10 TSH 0.03

08/09/10 TSH 0.01

09/23/10 TSH 0.41

10/28/10 TSH 1.36 -- T4 0.96

12/6/10 TSH 3.80 -- T4 0.92

12/28/10 TSH 0.99

02/11/11 TSH 2.45 -- Free T4 1.1
*****PUT ON 25 MCG of SYNTHROID*****

03/28/11 TSH 4.18 -- Free T4 0.9
*****PUT ON 50 MCG of SYNTHROID*****

04/28/11 TSH 0.6 -- Free T4 1.1

06/06/11 TSH 1.23 -- Free T4 1.2

06/14/11 *****PUT ON 25 MCG of SYNTHROID, 5 of CYTOMEL*****

07/07/11 TSH 2.91 -- Free T4 0.9

T3 Uptake 34 (Range 22-35 Percent)

Free T3 2.9 (Range 2.3-4.2 pg/mL)

Ferritin 51 (Range 10-154 ng/mL)

07/14/11 *****PUT ON 50 MCG of SYNTHROID, 10 of CYTOMEL*****

Here are my stats.  Can anyone offer any advice or opinion on my situation?  I am starting to worry because I have recently had my meds doubled and I still am sitting on the couch all day.  During the first four days of taking the 5 mcg of Cytomel I felt a lot better.  However, at the time I had also been on the 50 mg of Synthroid and I know it takes a while to build up.

Any thoughts?  I am still very lethargic and sometimes depressed, especially in the morning.  Every night I have a bad dream.  I am unable to exercise.  Do you think I will feel better if my levels are in the upper two thirds of the range (free t3/t4)?
2 Responses
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97953 tn?1440865392
MEDICAL PROFESSIONAL
With the negative anitbodies, it is not clear this is a long-term thyroid problem.  The pre-medication TSH of 2.45 was essentially normal.  Your lethargy may be due to relative changes in thyroid status but usually the TSH levels are much worse (higher) in these cases.  Titrating the medications may help, but looking for other causes would also be recommended.  Fatigue is a very common, nonspecific symptom and may not be thyroid related.
Helpful - 0
Avatar universal
THYROID AB (ATA,TPO)
THYROID PEROXIDASE AB <10 (RANGE: <35 IU/mL)
THYROGLOBULIN AB <20  (RANGE: <20 IU/mL)

GLIADIN AB (IGG) 3  (RANGE: <11 U/mL)
Interpretation: Negative
Helpful - 0

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