I am 38 years old and was diagnosed with Hashimoto's in Oct. '08. At the time, my tsh level was 16.3. I was put on 25 mcg of synthroid and initially felt some relief of my symptoms. If I take an honest look back over the months though, I haven't felt 'normal' and like myself in quite some time. FInally in early July, I couldn't take the symptoms anymore...depression, lots of anxiety, indigestion/bloating, fatigue, strange sensations in my hands and feet, so I went to the family dr. and asked her to check my levels. Sure enough, my tsh was high again, this time 7.4. She increased me to 50 mcg of synthroid, but I still was not feeling relief...if anything, my moodiness and anxiety is worse now! I finally got in with an endo yesterday. He said he would like to see my level between 1-2 and depending on the bloodwork results, he may put me on a dose as high as 100 mcg. I have two young kids and feel tired of feeling lousy and depressed. I want to wake up with energy, and not feel like I am going crazy! I want to enjoy my kids and life again!!! Anyone else out there dealing with a similar situation? Any advice, suggestions, would be greatly appreciated!