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347003 tn?1211996235

Hashitoxicosis or Something else?

I am very confused with the results of my comprehensive thyroglobulin tests. I was diagnosed with Hashitoxicosis in 11/07.  Was given PTU low dose for 3 months because my TSH levels were very low and my symptoms were really bad.  Three months later my TSH levels are down to normal. They've been ok for the past 2 months however my doctor still monitors me via blood work.  The latest tests taken on 5/1/08 showed Thyroid Peroxidase (TPOab) at a level of 1052.  TSH Receptor Antipbody (TBII) is 2.9 - Positive.  TSH Level is normal at .740
Why is the TPOab so high and what does it mean?  Not getting a very clear answer from my doctor.  
Anti-Thyroglobulin Antibodies is at 22 - Normal
Thyroglobulin (TG-RIA) is 13 - Normal
Triiodothyronine Free Serum is 2.9 - Normal
Thyroid Stimulating Immunoglob  is 89 - Normal

What is happening to me?
I still feel shaky sometimes and have heart palpitations. However, they are mild compared to what I felt like in November.
I've been having trouble with my eyes the past two weeks.  They feel kinda heavy all the time and they twitch several times a day every day. One eye sometimes gets blurry.  Does this have anything to do with my thyroids?
Appreciate anything you can tell me on this.
Thanks
2 Responses
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97953 tn?1440865392
MEDICAL PROFESSIONAL
This is Graves Disease.  The TPO antibody can be positive in Hashimoto's and Graves.  The low TSH is consistent with hyperthyroidism - the TBII c/w Graves as the cause.  Currently the normal TSH suggests things are in remission, but need to be watched as there are patients who progress to Hypothyroidism (a Hashimoto's like picture).  

The eye symptoms may be thyroid eye disease -- would consider evaluation by a neuro-ophthalmologist if this worsens.

This is all due to the immune system attacking the thyroid - and in the case of thyroid-etye-disease those antibodies cross-reacting with the fat/muscle in the eye socket.
Helpful - 1
347003 tn?1211996235
Thank you for responding. I will definitely be seeing an ophthamologist as per your suggestion.
Helpful - 0

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