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At what ALP level should I be alarmed after Papillary carcinoma?

I had my thyroid removed in 1999 because of papillary carcinoma that had spread significantly through the lymph nodes in my neck, & a resection in 2005 for recurrence, at which point we found out I am also iodine resistant.  My yearly (or more often) blood tests are always a little wonky but not alarmingly so. Now for the third year in a row my ALP is high & rising.  I have also had an aching thigh for several years, with no obvious cause.  My liver checks are all fine.  At what ALP level should we start looking into bone metastasis?
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