I have had oedema with various conditions but with hypothyroidism the fluid is notably in my abdomen and face.
Thank you Barb. I will definitely post labs when I get the results. The info about the free T4 is something I had not thought of but will research it further. I do regular weight lifting exercises, have been for years, but the arm flab has suddenly come on out of nowhere and is excessive (like my shirt sleeves are almost too tight in a matter of 6 weeks), so this makes me think it's hormonal and probably mostly water.
At 4.5 grains of desiccated hormones, I'd have to wonder whether your Free T4 is adequate, since it's common for people on desiccated hormones to have lower Free T4 and higher Free T3. I can't imagine that you'd need to add T3 with that much desiccated.
Being over medicated (too high Free T3) can cause fatigue and aches/pains, just as being under medicated can, but if you have and imbalance of high Free T3 and too low Free T4, you still aren't going to feel right.
The next thing I'd wonder about is the amount and type of exercise you get. Without proper exercise, it's not unusual for muscles to turn to flab... I've noticed my own arms getting more flabby than they've been, because I haven't been exercising adequately.