If nodule has blood vessels inside changing blood pressure can make it softer / firmer.
Is it common for a nodule to one day appear small, and then get bigger, and smaller again? Some days I can feel it pressing on my windpipe, and other days I can barely feel it at all. Any thoughts on this would be much appreciated!
Thank you for the response. I appreciate it! :)
The neoplasm is diagnoised if sample does not contain colloid material (colloid nodules have coloid and scattered follicualr cells).
Neoplasm contains sheets of follicular cells aranged in certain pattern.
Large amount of blood in the specimen (after needle hit blood vessel) may lead to incorrect diagnostics, so get the second opinion.
Thank you again! This is some really good information. I think a second opinion is necessary for me. Thank you for helping me understand all this!
Red_Star, Thank you so much for explaining that to me. I'm having a hard time understanding all the language in this report I have. The report does say no papillary architecture and does not demonstrate nuclear pseudoinclusion. Whatever that means. ENT doctor is wanting to remove 1/2 of thyroid to test the lump, but i'm just not ready for that. I'm thinking of getting a 2nd opinion first.
Neoplasm means is an abnormal mass of tissue. Follicular neoplasm is a "grey zone" in thyroid FNA cytology because of overlapping features between benign and malignant follicular lesions.
The reported incidence of malignancy in follicular neoplasm is 10 to 30%. The percentage is higher at 68 to 78% with very focal and subtle nuclear atypia commonly seen in papillary carcinoma.
I did find a study on pubmed "Routine second-opinion cytopathology review of thyroid fine needle aspiration biopsies reduces diagnostic thyroidectomy"..and cherry picked these two sentences...
"Some centers have shown significant discordance when a second pathologist evaluates the same FNA biopsy."
"A second opinion improved FNA biopsy accuracy from 60% to 74%. Overall, second-opinion cytology of indeterminate FNA biopsies avoided diagnostic operation in 25% (32/129)."