Dear Dr,
I am writng to you with questions related to my current illness. I am a 36 yr old male, with a past history of - Sept 94 - ? aseptic meningitis or ? meningoencephalopathy ( unexplained neuro illness lasted 2 -3 yrs ) was euthyroid on admission to hosp in 94. Only test that was positive was the ENG ( problem between eye and brain ) July 98- 1 episode of atrial fibrilation. Current illness started Oct 06 with a viral illness, subsequent symptoms on the last 1.5 yrs - Symptoms vary in intensity and duration, but they are as follows - heavy tiredness, muscle weakness, balance probs, anxiety, palpatations, muscle aches, joint pain, occassional strange explosions in my head ( feel like a split second stroke ), tingling sensations in my face and numbness in my hands, muscle twitches and cramps, hard to get up in the am, migraine headches, involuntary jerks, ? depression and seem to have CNS medication sensitivities. Also have had constant chest infection - pneumonia, and pleural effusion.
Med tests - prior to 08, SPECT Scan of the brain showed mild cerebral hyoperfusion post - cognitive challenge, tests post Feb 08 - TPO antibodies raised, but euthyroid. Was tried on a T3/T4 extract - caused major issues with activation symtoms. Was then tried on Lugols solution 3 drops daily. In June 08, t3 - 13, t4 37, TSH - 0.01, TPO 1500,
Thyroglobulin anti-body raised aswell, TSH antibody negative, thyroid ultrasound 3 small nodules, and sub -acute phase of thyroiditis ( Endo said nodules not of consequence ).
My question is Graves Disease ? Thyroiditis ? or is it possible that the neurosymptoms are related to raised TPO ?
Thanks Ganno.