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Hashimoto antibodies study article
Some interesting quotes on research results from a study in the journal simply called "Thyroid". This is floating around the web, I looked for the origional, was unable to find it on the web
Some quotes and re-quotes from About Thyroid :
["New research published in the journal Thyroid has shown that Hashimoto's thyroiditis, an autoimmune disease and the most common cause of hypothyroidism -- an underactive thyroid -- in the U.S., has an effect on quality of life. Specifically, the study found that even when the thyroid levels are "normal," Hashimoto's thyroiditis can increase symptoms and reduce the quality of life.............
...........In the study, researchers reported that among women with the same thyroid-stimulating hormone (TSH) levels, women who had higher levels of antithyroid antibodies had a substantially higher rate of symptoms...........
.........Charles H. Emerson, MD, Editor-in-Chief of the journal Thyroid, said: "This study raises important clinical issues..............it raises the possibility that optimal doses of thyroid hormone will not completely ameliorate all symptoms. Further studies are required to confirm the findings of Ott et al. and to determine if patients with hypothyroidism due to Hashimoto's thyroiditis still have residual symptoms despite achieving an ideal biochemical response to thyroid hormone replacement therapy."]
I found a copy of the origional document in a down loadable file, it points out the possibility of symptom differences between hypothyroidism and Hashimoto (antibody) hypothyroidism, so here is more from: www.liebertpub.com
THYROID
Volume 21, Number 2, 2011
ª Mary Ann Liebert, Inc.
DOI: 10.1089/thy.2010.0191
["......... symptoms like chronic nervousness
and chronic irritability are not typically related to hypothyroidism
or anemia. With this study, we are the first to demonstrate
that patients with elevated anti-TPO levels suffer
from a variety of general symptoms and a lower quality of life
despite euthyroidism. These findings are of striking relevance
since they shed new light on the clinical picture of HT."
"Another factor possibly contributing to Hashimoto-related
health conditions might be selenium. As mentioned above,
selenium supplementation leads to a decrease in anti-TPO
levels (14,15). Further, it displays antioxidant activity, antiinflammatory,
chemopreventive, and antiviral characteristics,
and is also known to directly influence immune responses
through its incorporation into selenoproteins (23)." ]
I have always wondered how they get participants for actual medical studies. For some reason men were not included in this study. Probably could not find enough to participate. But there were plenty that had general lack of motivation, hair loss, aches and pains, acid reflux, size XXL pants, heart problems, and held down the couch zoning out into space whenever possible.........oh, wait, those are Hashimoto symptoms arent they.........
Some quotes and re-quotes from About Thyroid :
["New research published in the journal Thyroid has shown that Hashimoto's thyroiditis, an autoimmune disease and the most common cause of hypothyroidism -- an underactive thyroid -- in the U.S., has an effect on quality of life. Specifically, the study found that even when the thyroid levels are "normal," Hashimoto's thyroiditis can increase symptoms and reduce the quality of life.............
...........In the study, researchers reported that among women with the same thyroid-stimulating hormone (TSH) levels, women who had higher levels of antithyroid antibodies had a substantially higher rate of symptoms...........
.........Charles H. Emerson, MD, Editor-in-Chief of the journal Thyroid, said: "This study raises important clinical issues..............it raises the possibility that optimal doses of thyroid hormone will not completely ameliorate all symptoms. Further studies are required to confirm the findings of Ott et al. and to determine if patients with hypothyroidism due to Hashimoto's thyroiditis still have residual symptoms despite achieving an ideal biochemical response to thyroid hormone replacement therapy."]
I found a copy of the origional document in a down loadable file, it points out the possibility of symptom differences between hypothyroidism and Hashimoto (antibody) hypothyroidism, so here is more from: www.liebertpub.com
THYROID
Volume 21, Number 2, 2011
ª Mary Ann Liebert, Inc.
DOI: 10.1089/thy.2010.0191
["......... symptoms like chronic nervousness
and chronic irritability are not typically related to hypothyroidism
or anemia. With this study, we are the first to demonstrate
that patients with elevated anti-TPO levels suffer
from a variety of general symptoms and a lower quality of life
despite euthyroidism. These findings are of striking relevance
since they shed new light on the clinical picture of HT."
"Another factor possibly contributing to Hashimoto-related
health conditions might be selenium. As mentioned above,
selenium supplementation leads to a decrease in anti-TPO
levels (14,15). Further, it displays antioxidant activity, antiinflammatory,
chemopreventive, and antiviral characteristics,
and is also known to directly influence immune responses
through its incorporation into selenoproteins (23)." ]
I have always wondered how they get participants for actual medical studies. For some reason men were not included in this study. Probably could not find enough to participate. But there were plenty that had general lack of motivation, hair loss, aches and pains, acid reflux, size XXL pants, heart problems, and held down the couch zoning out into space whenever possible.........oh, wait, those are Hashimoto symptoms arent they.........
But then these 'professionals' would have to believe what patients have been saying all along.
You think after awhile ( a long time ago) they would gotten the clue.
You think after awhile ( a long time ago) they would gotten the clue.
So it was a big revelation that patients who have achieved their definition of Euthyroid (which usually means that the TSH is midrange or thereabout) may still have symptoms. Wow, they could have just joined the Forum and become enlightened a lot easier. LOL
Maybe in a hundred years or so these docs will realize that there is more to TSH.
Maybe when we are all long gone they will understand how to treat better. It is so sad
to me that there are so many of us that suffer, despite a normal TSH level. It temps me to go back to school just to study thyroid. I would never trust the books though. The books are the ones that taught all those awful, awful endos out there!!!
Maybe when we are all long gone they will understand how to treat better. It is so sad
to me that there are so many of us that suffer, despite a normal TSH level. It temps me to go back to school just to study thyroid. I would never trust the books though. The books are the ones that taught all those awful, awful endos out there!!!
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