I was diagnosed with Hashimoto's thyroiditis in 2003. Within about six months of being on Synthroid and without changing my diet or exercise, I began to put on weight. I gained about 15-20 pounds in six or so months. While I was mentioning this to my endocrinologist, he kept saying it wasn't the medication. I had fasting glucose, glucose tolerance, cortisol, etc., testing but all is normal. My weight gain now is about five pounds a year---doesn't sound like much but now that I'm 43, it really is. Being 5'4" and 180 pounds is not good at all for me, when my max was about 140. I realize metabolic rates slow down as we age, but it also seems that I have to really starve myself for any weight to budge and exercise is kind of so-so on it all. Has anybody experienced weight gain AFTER Synthroid treatment for Hashimoto's? I realize the weight gain usually is a symptom, not a result. Thanks very much.