Have you heard about the thyroid med TIROSINT (Levothyroxine Sodium) capsules -- No DYE or FILLERS ? Dr. Lupo mentioned this med during his chat last night (link inside) ..

[ChitChatNine]

Tironsint Levothyroixine Sodium Capsules- no dye or fillers

Anybody using this med?  When did it come out - ?  

Dr Lupo's Health Chat 7/28/10:  http://www.medhelp.org/health_chats/show/52?camp=msc

[Barb135]

Kitchen_cook24 hasn't been active on the forum since her post on this thread, back in Jan 2011, so it's unlikely that you get a response from her.  

If you would like to start your own thread, since this is a very old and long thread, maybe we can help you figure out why you're having difficulties.

You can start a new thread by clicking the orange "Post a Question" button at the top of this page, type your question, then click the green "Post a Comment" button.  Or you can access the home page, via the following link and follow the same directions for posting a new thread:  
http://www.medhelp.org/forums/Thyroid-Disorders/show/73

[notime4cameras]

I'm the same way it seems. Have you found something that works?

[europeana]

I am using tirosint. It is awesome! The doc said he only trusts this med because this has the least fluctuation in the hormon strength. Its made in Switzerland by a company called Akrimax. It is also absorbed a lot better into your system since it is a gel cap. It looks like a small vitamin D. I will never go back to the generic levothyroxine. My hair was falling out I gained weight and felt awful until my doc put me on this medication. I felt the difference within 10 days.

[europeana]

I am using Tirosint. It is awesome! The doc said he only trusts this med because this has the least fluctuation in the hormon strength. Its made in Switzerland by a company called Akrimax. My doctor said the absorbtion is also a lot better also since its a gel capsule, Looks like a small vitamin D. I will never go back to other pills. I was feeling awful on generic levothyroxine my hair was falling out I gained weight I was tired and bloced up.

[Barb135]

If you are already pregnant, I'm not sure it's a good idea to switch. While some people have reactions to dyes and fillers in regular levo pills, they are not "harmful", unless you have a reaction and if you haven't yet, you probably won't.

The only difference between Tirosint and other brands of levothyroxine is that Tirosint is a gel cap, which dissolves more quickly and is supposed to have a higher absorption rate.  Some people find that they have to start Tirosint at a lower dosage because of the better dissolution and absorption.

No reason you shouldn't be able to take Tirosint during pregnancy.  As always, with pregnancy, make sure your thyroid hormone levels are tested monthly, throughout your pregnancy, because dosage may have to be increased, in order to insure adequate hormones for both you and the growing fetus.

[DJ1310]

Can anyone tell if tirosint is safe during pregnancy..
I'm planning to switch from generic levo to tisrosint just becuase I don't want to take harmful dyes/fillers during pregnancy

[NewVoyages]

I just started tirosint, have had headaches, panic attacks, pain in my lower abdomen, face numbness and muscle weakness. I'm on 100 mcg, feel better at night than during the day with an appetite at night but not during the day. Will be talking to my doctor tomorrow about this along with gastro problems and quick rise in BP's too. I'm allergic to all kinds of stuff, so additive free isn't always the best either I guess. So you aren;t the only one.

[codyc]

I switched to Tirosint from Synthroid over a year ago.  Switched to the same dosage and it was too much. I now take half of the amount of Tirosint that I was taking with Synthroid and doing much better.  My body absorbed Tirosint much better than Synthroid.

I really like Tirosint as my allergy problems with Synthroid have all gone away.

[Amk77]

I have been on 88mcg Tirosint now for 14 days, and I too have had chest tightness with heart palps. All my labs came back below the normal range. My dr now wants to switch me to Levoxyl. My symptoms are subsiding & I'd like to give Tirosint a little longer to work. Are you still taking Tirosint & how are you feeling?

[Anniegoose]

thank you for this wonderful dialogue on tirosint.

since i'm having sooo many problems with the levo, AFTER i go to the cardiologist [new heart problems since starting on the levo] i will ask about tirosint.


blessings to all.

[sunrock]

Thanks for your input. I am going to look into it.
Right now I am waiting ( hanging in there) for my 6 week test date and to level out on what I am on. I know I will most likely need to go up in at least the T4. The increase may be 115mcg from 110 mcgs.
I am wondering, I read from their web site that it is absorbed 103% over the pill form that is only 88% ....makes me think that I would do okay at 112 mcgs. But first I want to see how the blood tests for my Frees are
Mia

[laura1967]

I am on both:  150 mcg Tirosint and 25 mcg Cytomel. I take my Tirosint in the morning and half of my 25 mcg pill at same time. I then take the other 1/2 approximately 5-6 hours later.
My insurance reimburses me for the cost of synthroid, so i only have a small amount to cover on that one. It is well worth the cost to me!
Tirosint has been absolutely wonderful for me! I would never want to go back on any of the other T4 meds.  

[Barb135]

Yes, the T3 med is a pill; you can take it at the same time as the Tirosint, or not, whichever works best for you.  It would also depend on the dosage of T3 med.

I'm on 88 mcg Tirosint, with an additional 5 mcg generic T3.  I take my Tirosint when I first get up in the morning, then, since I'm on such a low dose of T3, I wait and take that later in the  morning.  Most people find it beneficial to split their T3 med into more than one dose, but again, because my dose is so small, it's not worth the hassle.  If you ask the doctor to prescribe the medication in 5 mcg pills, it's easy to split the dose, without having to actually cut the pills, thereby being able to keep your levels more steady.  For instance, if you were on 10 mcg/day, you could take 1 5 mcg pill in the morning, and the other around noon, or so, but it's best not to take T3 after about 3:00, or it could interfere with sleep.  

Check with your insurance company about the Tirosint.  My insurance pays for it, but not as much as they pay for a generic levo.  

[sunrock]

This is something I may look into as well. But I know I need T3 meds as well.

Isn't the T3 a pill? Do you take them at the same time?? Right now I am getting a custom combo capsule of T4 and T3...but my insurance will not pay for it like they gladly will  for synthriod.

If my insurance pays for this Tirosint....and I take a T3....it may not only work better but be more affordable!!!

Always hopeful in CA
Mia

[Barb135]

I've been on Tirosint, since shortly after it came out in May 2010.  It's certainly not a "placebo".  

I was on levo pills for over 2 yrs, prior to being on Tirosint, and once I got on it, there was immediate improvement.  Ovviously, "liquid Synthroid" is something to see for some of us.

[DreamNaut]

Beware of placebo ladies and gents, I would ask an honest pharmacist about the drug before switching :)

[DreamNaut]

Seems like a good medication for those with allergy to Synthroid fillers, but there is nothing revolutionary about this drug. Yes it may 'absorb' a little bit better / quicker, but if you take your Synthroid like you should, on an empty stomach with a full glass of water, it's not worth switching over unless your just doing TERRIBLE on Synthroid, even then I might recommend Armour. IMHO, nothing to see here, liquid Synthroid..

[Barb135]

Because of the better absorption of Tirosint over pill type meds, some people who have been on pill type med, may need to drop down a notch when they take Tirosint; however, that's not always the case and the same dosages are available for both types of med.

I agree that scary is most likely over medicated and should probably cut back her dosage.

[flyingfool]

Thank you for the clarification.  I thought I had read that the Triosint capsules were 88 mcg for example instead of 100 mcg Synthroid because of the better absorption of Triosint so they would have the anticipated identical final result.

Good.  Learned something new today.

But the thought that if she was on 137 mcg or Synthorid and if she is taking the same 137 mcg of Triosint, with the better absorption the already high T4 may have gone up even higher, resulting in hyper symptoms for her I think still seems sound.  

Reaction seems fairly fast but she may have been on the edge of hyper to start with and this just pushed her over the edge.

[Barb135]

It sounds like you might be over medicated, and possibly need to drop your dosage of Tirosint.

flyingfool - your understanding of Tirosint is incorrect.  The pre-manufactured dosages of Tirosint are equivalent to either Synthroid or generic Levo.  They are NOT different or smaller.  No matter what the brand, the amount of medication is the same (i.e - 100 mcg is 100 mcg - it's just a difference of pill, with fillers/binders vs gelcap w/o fillers/binders.)

"Tirosint is available in 13 mcg, 25 mcg, 50 mcg, 75 mcg, 88 mcg, 100 mcg, 112 mcg, 125 mcg, 137 mcg, and 150 mcg dosage sizes."

These are the same dosages available in Synthroid or other brands.

[flyingfool]

Synthroid & Triosint are both pure T4 meds.  So from a hormone and chemical standpoint they are identical. So drug interactions would likely also be identical unless the drug interaction is caused from the fillers in the Synthroid and Triosint has no fillers or dyes.

You're symptoms of hot & sweaty indicate that you may have switched over to being Hyper.  Due to the fact that Triosint is a liquid type cap and not a dry pill. The absorption of Triosint is higher than synthroid. I understand the premanufactured doses of Triosint are different and smaller doses than synthroid for this reason.

Your lab results show you to be near the very top of the range for FT4. So with the addition of a higher absorption or efficiency of the Triosint it I suppose is possible that the FT4 level is even higher now.

What was the dosage of synthorid (137 mcg I think) and what is the dose of Triosint you are taking now?

T4 meds are usually slow acting so it is a bit odd for you to suddenly go Hyper in a few days.  May be some other allergic reaction or something to the medicine itself.

Do you have your lab results of where you felt good on the T3 Cytomel only regiment?

It also appears that you have only a TOTAL T3 lab result and not a FREE T3 test done.

[scarytimesjanuary]

6 weeks ago I had a total thyroidectomy for multiple but localized pap carcinoma. I was on cytomel for 2 weeks and loved it. They took me off. Guess it is too hard on the pituitary with the up and down daily blood level swings.

Then they switched me to synthroid 137 micrograms. I weigh 140. I felt like hell. Depressed, crying, mood swings, wanted to jump out of my skin when I went to bed at night, not my normal althetic energetic self. 4 weeks later I had just started feeling a little better, but switched to tirosint in hopes that it was a better product. Had my labs checked same day. Results:

TSH was .06.  ref range .4-4.
Free T4 was 1.6     ref range .8-1.8
T3 98                      ref range 76-181
Thyroglobulin 3.3    ref range 2.0-35
TG antibodies <20  ref range <20

I think they want my TSH between .2 and .5

5 days later i feel terrible! Not sure what it is from. I am in bed for the last two days. Hot all the time, when I am normally not so. GI distress. Malaise, queezy, like I have a flu without the muscle and joint pain. I might have guessed it is from too much salt intake over the weekend and that affecting my inner ears, but I am sweating and the windows are open. Yes it is Texas, but it it not that warm here.

I read that Tirosint should not be taken with SSRIs, yet I take cymbalta. I am wondering if synthroid also should not be taken with SSRIs.

Any thoughts?

[Alvarel]

I am new to hypothyroidism and I am not sure what my test results were to list right now but I started on Tirosint 75mg on Tuesday and I've been feeling so horrible!  I am not sure if it's the meds or a coincidence that I started getting sick the same day I started the meds.  I ended up in the ER a couple of hours after taking it with shortness of breath, chest tightness, tension headache, diarrhea, unquenchable thirst, dry mouth, my heart was fluttering and extreme fatigue.  I've been this way the past few days and my Endo said to keep taking the medicine.  I don't know what to do, as I stay home with my 2 yr old and just can't feel like this when I'm home alone with him.  Is this normal or could something else be wrong with me?  ER thought maybe allergies, went to Allergist today and it's not allergies, I do have an appt. with my PCP tomorrow and really hope it's something else that's curable ;) because I really really want Tirosint to work and I really want to start feeling better already!!

[adri326]

Thank yeah I definitely plan to have her order free T3 next time, I'm not sure why but she never does. But my high TSH (when it almost tripled to 1.88) was while I was still taking Armour, right before I switched. I haven't had any labs done since switching. That's why I was so surprised because I've heard Armour really supresses TSH.

I guess I just thought 7 wks would b enough time to see some kind of improvement, but instead I've gotten worse...