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High thyroglobulin level & increase in goiter size

My 56 year old husband has an upcoming biopsy due to a 30% increase in goiters his doctor has been watching for last 6 years or so. His most recent thyroglobulin level, from a test last week, is 1445.7. That seems very high. Please, any advice would be appreciated. We are both very frightened that it is cancer. We know there are other thyroid disorders. He has always been asymptomatic, except for recent occasional pressure in his throat.
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