Hypothyroid and Methotrexate Problem

[lmarie3]

Hi,
I was on oral Methotrexate for SLE, my synthroid dose was at 175 then lowered to 150 just prior to the Methotrexate. over 6 months has went by and DR did not check TSH after lowing dose or while I was taking the Metho, now my TSH is at 67.9. Needless to say I am not feeling very well. Can the Methotrexate alter my thyroid levels? I am off Methrotrexate now and  only taking 5 mg of Predisone and 175 synthroid?

[losingfaith63]

No but i need to know the answer

[lmarie3]

Thank you for answering, I did ask for another lab work up because he did not do the free T4 and T3 which concerned me. I am starting to think he is "dense"  I go to my endo next week so I was trying to have all the information together that she will need to get this under control again and find out what went wrong. I was wondering if Methotrexate could have an adverse effect on dosage as well as the predisone? I can not seem to find any studies or information on it..
Best
Lmarie3

[laura1967]

Steriods can have an affect on your thyroid levels. I would ask for another lab check, because if you are still at a 67.9 tsh, then you are going to need more meds. Next question, what is your Free T4 level?? The free T4 and Free T3 levels are your actual thyroid hormone levels. TSH is a pituitary function test and cannot be used alone to treat your thyroid.