Ok, here goes.... In 2006 I started feeling fatigued, depressed, weight gain, took every bit of energy I had to go to the gym. *NOTE* prior to this I was a very active, happy, thin individual. So, I started seeing my Doctor, blood work was done, he said everything looks normal. My symptoms continued to get worse, then got fibermyalgia. Doctor continued to have blood work done "normal". But, I wasnt, I kept telling him something was wrong. Finally, he put me on levothyroxin 25mcg. Continued blood work, still readings were normal. Symptoms continued to get worse. At one point he sent me in for a brain scan, Pituitary "normal"/ more blood work. I go into see him, he states "I'm confused, your blood work is telling me to decrease yours meds, brain is telling me to increase your meds. At that time I was taking 175mcg levothyroxin and 25mcg cytomel. So, Aug 2009, he sends me to an Endocrinologist. She does blood work, checks to see if my body is absorbing meds, it was. She takes me off cytomel and switches me to sythroid and ups it to 200mcg. I started feeling better, weight started dropping. Went back for 3mo check, blood work said hyper, but Endo went with my symptoms and left med at 200mcg. Went back in Jan 10, blood work said hyper, she lowered dose to 175mcg. Within a month hypo symptoms returned, so Endo put me back on 200mcg. So, Dec 2010 I was still feeling like myself. TSH 11.40 (range 0.30-5.27) Free T4 1.00 (range 0.8-1.8). Then July 2011 I started feeling hypo symptoms again. So, I went to see regular Doctor and he scheduled me to see an Endo. Aug 2011 blood work TSH 0.04 (range 0.49-4.00) Free T4 1.36 (range 0.60-2.00). She immediately dropped my dose to 175mcg, I tried to explain to her what would happen. She didnt want to here it. Started stating bone loss, heart problems that will happen if TSH continues to be this low. So needless to say I left her office feeling extreme anxiety. I knew what was coming. Went back and had blood work done Oct 2011. TSH 1.67 (range 0.49-4.00) Free t4 0.37 (range0.60-2.00). I told her how bad I was feeling, she refused to understand and said she is leaving me on the meds she prescribed. I fired her. Now it's Jan 2012, I feel horrible, have put on 12lbs since Aug and for no reason. Went back to my Primary Doc, he put me back on 200mcg. Said he will go by my symptoms, not blood work. I will post updated blood work as soon as I get results. I have been back on 200mcg since Nov 2011 and it doesnt seem to be working. Soooooooo????????