I have had low thyroid for over 25 years. My first 22 years I was prescribed Armour Thyroid and did quite well on it most recently taking 90mg. Armour is not covered by insurance so eventually my doctor recommended I switch to Levothyroxin 100 mcg. After taking it for 2 years I gradually noticed symptoms returning, loss of hair, no energy, extremely dry skin and moderate weight gain. My new doc ran a thyroid panel: TSH 2.17, T4 was 10.3, T3 uptake 31.9, T3 total 68 (low). So doc changed my prescription to 75 mcg Levo and 1/2 a 25 mcg T3 1x a day. Day 6 of new script I apparently had an allergic reaction with mild swelling of inside of my cheeks and lips. Poor doc was frustrated, and had me stop the T3 but wanted me to go back to Levo 100 mcg which wasn't working either. I have continued the 75 mcg Levo, stopped the T3, but still have the mild swelling. Now, to complicate things, about Aug. 2019 I began having muscle pain in all hip, butt and thigh muscles gradually limiting my movement. I also started experiencing pain in my shoulders and all upper arm muscles eventually becoming disabling. Doc was stumped. Thought the thyroid changes might help, didn't. He did take xrays of hips and shoulders. Perfect. An MRI of low spine showed nothing remarkable that could cause the pain, just minor age related issues. Unfortunately, I started taking Aleve for the first time ever to take the edge off my pain so I could function and after a few days I got moderate swelling in my lips causing them to become very chapped and cracked. I stopped taking Aleve and a short time later changed my thyroid script. My lips are still a mess plus the added swelling in my cheeks. HELP!!! I do have an appt with an Endo. doc but not till mid Feb. I read that some have a reaction to the coloring in the different strengths of Levo. Mine is now Lavender instead of white. How rare are reactions? By the way, I'm 77 years old.