Aa
Out of control
My peroxidase level was over 1000 when I was first diagnosed two years ago. Now it is 529. My tsh t3 t4 are within normal limits. I take 112mcg of levothyroxine daily and watch what I eat yet my symptoms are TOTALLY out of control. I'm always fatigued and have not energy, I have gut issues and just an over all feeling of malaise. Is it ever going to be possible to get this under control and get my peroxidase levels with in normal limits?
Your FT4 is actually a little on the high side. It's 88% of range, and the target for FT4 is about 50%. FT3 is at 49% of range, which is very respectable, but still a little short of the upper half of range recommended for FT3.
If I were you, I'd ask my doctor about dropping your levo dose a bit and adding in some T3 (Cytomel). Ideally, you want to see FT3 a little higher (as a percentage of its range) than FT4 is.
The rule of thumb when adding T3 is to drop T4 meds by about 25 mcg for every 5 mcg T3 you add in. Since your FT4 is already on the high side, I'd drop it at least 25 mcg. You'll want to start off slow on T3 since it's more potent and active than T4. Considering your labs are very close to target, you might want to ask your doctor about 5 cg daily, split into two dose, usually one first thing in the morning, the other late morning to early afternoon, but not late enough to impact sleep.
If I were you, I'd ask my doctor about dropping your levo dose a bit and adding in some T3 (Cytomel). Ideally, you want to see FT3 a little higher (as a percentage of its range) than FT4 is.
The rule of thumb when adding T3 is to drop T4 meds by about 25 mcg for every 5 mcg T3 you add in. Since your FT4 is already on the high side, I'd drop it at least 25 mcg. You'll want to start off slow on T3 since it's more potent and active than T4. Considering your labs are very close to target, you might want to ask your doctor about 5 cg daily, split into two dose, usually one first thing in the morning, the other late morning to early afternoon, but not late enough to impact sleep.
Thankyou for your response. The lab values I have are as follows: FreeT 1.33 (0.76-1.46), Free T3 3.06 (2.18-3.98), TSH 0.127 (3.58-3.74), Peroxidase Antibodies 529 (0-60). Let me know what you think.
If you still have all those hypo symptoms, then your meds are not properly adjusted. Please post recent thyroid lab results and include reference ranges from your own lab report. We can take a look and give you an idea of which direction to go in.
It would be very rare for you to get your TPOab levels back into normal range. Once we have antibodies, we have them for life. However, once the thyroid is functionally "dead", surgically removed or irradiated, they can go into remission. The antibodies are not what's making you feel bad. It's the resultant inability of your thyroid to make hormones and your meds that are causing your symptoms.
Please post your results, and we can get started.
It would be very rare for you to get your TPOab levels back into normal range. Once we have antibodies, we have them for life. However, once the thyroid is functionally "dead", surgically removed or irradiated, they can go into remission. The antibodies are not what's making you feel bad. It's the resultant inability of your thyroid to make hormones and your meds that are causing your symptoms.
Please post your results, and we can get started.
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