Has anyone had an allergic reaction, intense itching and little itchy blisters from pores, when they started Tirosint ? I have had the itchy blisters for a while that come and go ever since my thyroid went south but the over-all itching is new and the increase in blisters is awful. Ingested antihistamines don't help. Benedryl spray helps a little. Topical cortisone, not at all nor topical anti-fungal. My dose went from 75 mcg Mylan levothyroxine to 88 mcg Tirosint. Why does Tirosint come in such a strange dose anyway ? It seems hard to believe I would have an allergic reaction to the most pure hypoallergenic version of T4. I have been on it for nearly 2 weeks. The reaction was immediate. I'm starting to think I'm allergic to T4, period, since I cannot get better after 8 years of trying.
Turns out that WPThyroid is covered under my insurance and the doctor is willing to prescribe it. My current doses of thyroid meds are 88 mcg Tirosint and 35 mcg Cytomel. How would I convert that to the dessicated thyroid. Obviously I would still have to take extra T3.
Only recent progress is that one of the 3 new doctors that I've seen since May (2 "integrative, anti-aging, geriatric but AMA as well", one a regular general AMA practitioner who claims knowledge in thyroid dysfunction) finally ordered the MRI of my pituitary I have been asking for since 2005 and gee, imagine....pesky little pituitary adenoma. Think that's why my TSH is so low, idiot doctors ? Why my circulating thyroid hormones are so low too ? I've told every doctor I've seen, including at the pituitary center at Cedars in LA, that this all started after bad whiplash and herniated disc car accident and has only gotten worse as that accident has been compounded by others causing more head trauma But, you know, the MRI doc says he doesn't know how to "treat" it, has no referral for me, and basically sent me back to the woman who referred me to him, telling me I needed an ACTH-stim test but that he couldn't do it and wouldn't know how to interpret it. My serum ACTH test was abnormal. Now the doc that gave me the Tirosint is insisting that I have to do a 24 hour urine cortisol test before she will give me the stim test.....OK, I had one done back in 2010 at the pituitary center. It came back high out of range but I was told it was "fine" and that I needed to stop taking thyroid medication immediately or I was "going to give myself a heart attack and dissolve my bones" even though my bone density had gotten better with the addition of T3 and a stress test and blood markers showed my heart was fine. at that point my PCP started giving me the T4 and T3 I asked her for, since no endo would, and blood testing me every 6 weeks to adjust the levels. at 150 mcg T4 and 30 mcg Cytomel my levels were where it seemed they should be ...FT4 at 1/2 the range, FT3 in the upper quarter....but edema was worsening, I was getting random spasming in my feet and an occasional charleyhorse in my calf, and I started gaining weight and having GERD symptoms and abdominal bloating. So my PCP said she didn't know what to do and said I had to go back to endos, and then she retired and closed her office. I am SO lost.
Anyway, so I did the 24 hour urine test again but the doctor's office neglected to tell me to throw the first am sample away....and then, after I researched how to interpret the results and found out the protocol was violated, the nurse at the doctor's office told me"That's the way we always do it, you collect everything in 24 hours." I told her she'd better check with the doctor and the lab. whoops. How many other patients have been mis-diagnosed by this office ? My 24 hour saliva test for cortisol was abnormal, high in the am and falling off rapidly in mid-day, then rising in pm but not to optimal levels.
I just keep getting worse....gained 25 lbs in 2 months, 4" around the waist, and everything hurts and my hair has fallen out again. I am 50 + lbs over my formerly stable lifetime weight, yet have no appetite. My cholesterol has soared along with my blood pressure.The edema is fierce. One of the most recent docs wanted to immediately put me on statins and Prilosec, even though that's usually contraindicated for thyroid. When I told him I
d been on Prilosec before and it did nothing, only T3 made the gerd-like symptoms go away, he told me he wasn't interested in my past. He found that I have MTHFR 1298 cc, but had no idea what that meant. I see the other stupid doctor tomorrow and at least want her to give me a script for SOMETHING so I don't die while looking for yet another doctor. Let's see....so far 6 endos, 2 dermatologists, 3 other "thyroid specialists", 1 gastroenterologist, a neuro-hearing doctor because of the ringing in my ears blahblahblah. Please shoot me, but not before you give me the WPThyroidd conversion formula.