What does a test result of 21 mean. The P. A. that gave me the result just said my result was "21". I have been on levothyroxine since 1985. I currently take 250mcg per day. I am gaining weight at an alarming rate, and have no energy, thin nails, hair loss in the extreme(most of my body hair is gone, and the hair on my head is getting thinner), I can't sleep for more than 6 hours, (when I can sleep, awake, of and on all night), my muscles hurt all the time. My face looks like it's been inflated. My P.A. told me the test result was 21, but said nothing about my medication.