estriol for hashimoto's?

[Liz118]

Has anyone tried taking estriol for hashimoto's thyroiditis?

[Liz118]

That is the study I was referring to...
I would love to hear from Dr. Lupo about this, too!

[estrelinha]

I found some papers related to estriol treatment:

""The mechanism by which sex steroid hormones might direct modulate immune cells or autoimmune processes is not completly understood" (2005). Curr. Med. Chem. – Immun., Endoc. & Metab. Agents, 2005, 5, 85-91.

There are studies that are being carried out to understand why women have more autoimmune diseases, and they think it's related to hormones. It is used in MS (studies)

And :
PREGNANCY HORMONE MAY TREAT MS :
--------------------------------------------------------------------------------

Experts have long known that women with certain autoimmune diseases – including multiple sclerosis, rheumatoid arthritis, and Hashimoto’s disease – have fewer symptoms, or even remission – during pregnancy. Based on this observation, researchers at UCLA conducted the first trial of hormone therapy specifically targeted to MS, and found that estriol, an estrogen hormone that is produced during pregnancy, may be a treatment for MS. In a preliminary study, the hormone, given in a pill form, was found to reduce symptoms in a group of women with early MS. The hormone could eventually provide an alternative to injectible anti-inflammatory drugs used for MS.

After six months of treatment, the women with the early MS were shown to have less brain inflammation. Improvements disappeared when the women were taken off the estriol, and improved again back on the hormone. The hormone did not help those with more advanced MS.

Additional studies are likely to take place to look at effectiveness, and longer-term safety of estriol, which is used widely in Europe, but not typically in the U.S.

Source: Annals of Neurology, September 2002

I live in Europe, I believe in MS it is used but in hashi ???
I think it is a good question to ask Dr. Lupo, what he thinks about this.

[estrelinha]

Do you have a reference about that, it's new to me about Hashi.

[Liz118]

Estriol in high doses has been shown to work as a treatment for automimmune diseases such as multiple sclerosis and hasimoto's thyroiditis
Thanks!

[estrelinha]

Estriol is not a treatment for Hashi, it is one of the three major naturally occurring estrogens.