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973594 tn?1247951791

reverse t3 and normal temps

People pardon my ignorance but is it the same high reverse t3 and thyroid resistance hormone? How can someone have a high reverse and have normal temps between the 97.8 to 98.2? My doctor refuse to give me t3 if my temps are this high. Is it wilson's low temperature the same as having resistance to your hormone replacement and not getting it into your cells?
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Avatar universal
Really, that is all you can do...this is such a waiting game and requires patience, patience, and more patience.  Actually, when I was hypo, that was one of my main complaints...I wasn't tired or fatigued, and as long as I kept moving I was fine.  However, the minute I sat sown (car, computer), I started to nod off.  I literally could not keep my eyes open.  Give it some time...
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Avatar universal
my, that is quite a question.  i would have to say worse, definitely.  getting tired is one thing, being able to hardly keep the eyes open is another.  

oh well, the allergies are crazy around here right now so could be kicking in.  letting it ride and we'll see.

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Avatar universal
Are they really worse, or worse compared to how good you feel just after you've taken the combo?  It's all relative...

Once your FT4 has time to build, that may resolve itself.
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Avatar universal
thanks bunches...yeah, it's too early.  except that the energy lapses got worse after being on this for a bit.  acckkk  today was a rare day that I didn't take a nap on a weekend day but was careful to take protein on time and med too.  we'll see and thanks for the patience.

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Avatar universal
Oh, in that case, it's too soon for labs.  I didn't realize you had just started that recently.  Your T4 levels haven't even had time to stabilize yet, and often adequate conversion takes a wile after that to "kick in".  Well, keep us posted on how things look (and how your energy lapses are going) once you have further bloodwork.  
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Avatar universal
Nope...just started 3/25 so not due yet for lab tests for evaluation.
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Avatar universal
So, you just started your meds within the last few weeks?  Haven't had your first re-test to evaluate what meds have done yet?
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Avatar universal
They are the most recent labs.  New dr recognized it for what is is and worked from them.  This is the initial dose. I've fought for years to get this far.

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Avatar universal
Are those the most recent labs you have?  How long have you been on the combo?  Any dosage increases, or is this your initial dose?
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Avatar universal
This is the first time am on any thyroid med, no switch was involved.  
Yes, have had lunch when this occurs typically.  I eat on the low-carb side most of the time.  

If it were about taking the med often enough during the day, then I'm not on a high enough dose to fit that in well.  30mg capsule of compounded dessicated thyroid.  

8/17/09 Tests-
TSH      0.760             0.46 - 4.7 range              
FRT4     1.27              0.89 - 1.76 range          
FRT3     2.70              2.3 - 4.2 range              
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Avatar universal
How much T4 were you on before the switch, and what's the T3/T4 ratio in your new combo?  Why did you make the switch?

You're right...all you can do is experiment with what works for you as far as timing is concerned.  Have you had lunch when your energy level drops?  Depending on what you eat (protein vs. carbs, etc.) you might play with the timing of that a bit, too.  How's youe energy at the end of the day?  Do you feel like you can move the second dose to an earlier time and still make it through the whole day?
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Avatar universal
I appreciate the input.  I'm thinking it's that the body is getting accustomed to the T3/T4 med I'm taking and in doing so, come 12p or 1p my energy level drops like there's no tomorrow.  Haven't yet been able to test enough to see if it's the thyroid med wearing off or hitting hypoglycemic spots.  I mean I can literally barely keep my eyes open which of course isn't a good combination when at work.  

I can't split up the Ts of the med as it's all in one med.  I have split up the med into twice a day but need to check further if the extreme tiredness is occurring because I haven't taken the second dose soon enough to ward off the problem.

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Avatar universal
T3 is very fast-acting and quickly eliminated from your system if not used promptly (a few hours).  So, if you don't split the doses into at least two, you usually end up with "peaks and valleys" of energy.  As you said, you feel good after taking it, but will fade later in the day if you don't have another half dose to take.  Everyone's a bit different and has to experiment for themselves when the best time is to do that.  Often, it's late morning or early afternoon, but not late enough to affect sleep.  Some people also find they can just take their T4 meds first thing in the morning, wait a few hours and take the first half their T3, and then take the other half in the afternoon.
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Avatar universal
question?  how do you feel if your T3 isn't kept consistently throughout the day?  I mean, I realize one feels good when it's taken first thing in the morning.  But, what about later in the day if you go too long without taking the next dosing?

curious at the results.

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Avatar universal
Check out this link on RT3 dominance.  The article says that you have to use time-released T3, but I've heard others on the forum say that TR T3 is junk and you have to take regular T3 in very carefully timed doses.  Also, if you're only taking T3, you are going to have to spread it out into several doses during the day so that your hormones stay at a relatively constant level (and, therefore, so does your energy).  It's tricky, and I really would advise you to wait until you see your new doctor before trying anything on your own.  I can't really advocate self-medicating no matter what the meds, but with T3 I'd be even more cautious.  It's much more potent than T4, and you can get yourself into trouble pretty quickly if you're not careful.  

http://www.custommedicine.com.au/blog/2007/04/17/reverse-t3-dominance/
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973594 tn?1247951791
My hypo symptom is only hair shedding, big time, can see my scalp by now, that's my cue that something is not well, nothing else.
My rt3 was 351 with a top range of 350 and my free t3 2.5 ranges 2.00 to 4.4 although that's always my usual range with t3 I suppose that the rt3 is too high and obviously interfering with it. I gave up waiting for a doctor to give me t3 so I just order it over the net and will start to try it in very low doses. Any idea what the lowest dose could be? I'm presently taking 100mcg of levoxyl.
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Avatar universal
Have you had RT3 tested?  If so, what was your RT3 result and FT3 result from the same draw?

T3 is a bit trickier to use than T4 because it's so fast-acting.  You have to take it several times throughout the day so that the level stays somewhat constant.  It is really frustrating, though, when doctors just keep trying the same old thing that doesn't work.  Do you still have a lot of hypo symptoms?
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973594 tn?1247951791
I tried in the past natural thyroid and even I went up to 3 grains my ft3 only hit 2.7 max, my normal fr3 is 2.5 with synthetic t4 so it only went up 2 points,  why I have no idea but is curious, would I be having the same problem if I try cytomel? I also read that many people don't respond to only t3 therapy and is a very vulnerable life you live while on it. My doctor don't want me taking cytomel and I'm at my wits end, I just call a new endo and book an appmt for may 17, that's the earliest they have, I haven't had much luck with endos but I don't know what else to do at this point, I can't believe how difficult it is to find doctor willing to change treatment, I guess I'll have to keep on trying.
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Avatar universal
I've done a fair amount of reading on RTH because I have pituitary resistance to thyroid hormone (PRTH).  My resistance is limited to the pituitary and keeps my TSH artificially high.  There is also peripheral resistance to thyroid hormone where the cells cannot use T3 except when it's in massive quantities, i.e. FT3 in way, way, way above range.  This is by and large a genetic condition, so doubt it has to do with T4 meds..

RT3 dominance:  the liver converts T4 into both T3 and RT3.  RT3 is inactive, but a mirror image of T3, so it can "dock" at the receptors in cells "upside down".  RT3 is not metabloized by the cell as quickly as T3 would be, so it stays in the cell and "blocks" the T3 from docking there.  Therefore, cells cannot get any T3, and even though your FT3 may be "normal" you feel hypo because your T3 can't do you any good.  I don't recall ever reading about a cause, but my personal suspicion is that T4-only meds would seem to contribute, if not cause.  Once RT3 dominance comes into play, increasing T4 meds can just make the situation worse by increasing the RT3 even more.  Higher RT3 levels apparently stimulate even more RT3 production.  The therapy is usually a temporary course of T3-only meds (several weeks) until the RT3 is cleared out of cells and balance is restored.  Then, T4 meds can be reintroduced either alone or in combo with T3 mdes.
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973594 tn?1247951791
  I read that people on synthetic t4 for a long time can develop resistance to thyroid hormone, is that true? yes, that was my question, would you care to explain to me please what is the difference between them?
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Avatar universal
Wilson's syndrome and RT3 dominance are the same thing.  Resistance to thyroid hormone is a different condition altogether.  I'm not sure if that was your question...?  As with all hypo symptoms (and RT3 dominance makes your hypo), symptoms vary per individual.  
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